# Shared Resources Core-1: Integrated Clinical, Tissue, and Biomarker Data Base Core (ICTBD Core)

> **NIH NIH U54** · CHARLES R. DREW UNIVERSITY OF MED & SCI · 2022 · $120,655

## Abstract

ABSTRACT (Shared Resources-ICTBD Core) 
The overall objective of the Integrated Clinical and Tissue Biorepository/Biomarker Data Base (ICTBD) Core is 
to enhance and upgrade our current ICTBD Core which is integrated with our Clinical Resource Core. This will 
be accomplished through a multi-dimensional translational research approach which leverages the 
Partnership's research/outreach Cores, clinical networks, community partners, and academic partners 
developed through the 1st U54 funding cycle (2009-2015). The Partnership uses Translational Research 
according to the two translational blocks (T1- Basic/Biomedical Research and T2- Clinical/Implementation 
Research). During the 2nd U54 Cycle (2015-2020), the Partnership proposes to utilize the ICTBD Core to both 
enhance existing T1 activities, and facilitate the transfer of projects developed in 1st U54 cycle from T1 to T2. 
We will accomplish this through the following: 1) continue building networks to enhance biospecimen/data 
collection and facilitate translational research, 2) provide patient consent/engagement into biospecimen and 
clinical research protocols, 3) facilitate a platform of bi-directional exchange, education/training, and 
information dissemination between the Partnership's T1/T2 activities and the Community Cancer Outreach 
Core, 4) provide administrative support for T1 to T2 transition such as IRB preparation, monitoring, and patient 
recruitment to enhance underrepresented patient participation in clinical trials, and 5) work in partnership with 
our community partners and community oncologists to continue to build and sustain a comprehensive 
biospecimen repository with focus on breast, colon, and prostate cancers from African Americans and Latinos 
for the purpose of identification of novel markers for assessing risk of cancer incidence and progression that 
may be unique to ethnic groups and reduce cancer health disparities. These activities will dually enrich both 
sides of the CDU/UCLA Partnership by bolstering CDU's institutional capacity for translational research with 
UCLA-JCCC resources, and diversifying access for UCLA-JCCC to improve engagement of underrepresented 
participants in research.

## Key facts

- **NIH application ID:** 10680622
- **Project number:** 3U54CA143931-10S3
- **Recipient organization:** CHARLES R. DREW UNIVERSITY OF MED & SCI
- **Principal Investigator:** Jaydutt V. Vadgama
- **Activity code:** U54 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $120,655
- **Award type:** 3
- **Project period:** 2009-09-29 → 2023-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10680622

## Citation

> US National Institutes of Health, RePORTER application 10680622, Shared Resources Core-1: Integrated Clinical, Tissue, and Biomarker Data Base Core (ICTBD Core) (3U54CA143931-10S3). Retrieved via AI Analytics 2026-06-08 from https://api.ai-analytics.org/grant/nih/10680622. Licensed CC0.

---

*[NIH grants dataset](/datasets/nih-grants) · CC0 1.0*