This Supplement proposes to add an underrepresented Scholar, a physician-scientist of Hispanic origin, to the UIC BIRCWH program. The Scholar is a tenure-track Assistant Professor in the UIC Department of Family and Community Medicine and leads a program of research focusing on health disparities in cervical cancer. The Scholar's Primary Mentor is a well-funded Professor of OB/GYN and former BIRCWH PI with a strong track record of research on women's health, including an ongoing project with the Scholar on health disparities in cervical cancer screening where they serve as Multi-PIs. The new Scholar will join the current BIRCWH cohort of three Scholars, including two MDs and a PhD of Hispanic origin. The overall goal of the UIC BIRCWH Program is to align with the 2019-23 Trans-NIH Strategic Plan for Women's Health Research to “promote training and careers to develop a well-trained, diverse, and robust workforce to advance science for the health of women” (NIH ORWH, 2019). Our long-term objective is to promote training and career development of a new generation of researchers equipped with the knowledge and career skills necessary to advance science for the health of women in the next decade and beyond. We are based in the UIC College of Medicine, but draw on the interdisciplinary strengths of UIC's seven health colleges. Our past success directing a BIRCWH from 2007-2017 fostered the academic careers of 18 Scholars (33% under-represented minorities; URM). We also have a record of success mentoring in the UIC-funded Women's Health Research (WHR) Associates Program which supported 8 Scholars (38% URM) and the UIC-funded Bridge Program which supported 3 Scholars. All three programs have received strong institutional support from UIC leadership. The 2019-2024 BIRCWH aims to train 6 junior faculty researchers in women's or sex/gender-based health research: 3 MDs for 3 years and 3 PhDs for 2 years. We capitalize on four program strengths: (1) our success in launching the careers of 29 junior faculty in women's health research; (2) alignment with the Trans-NIH Strategic Plan for Women's Health; (3) the highly interdisciplinary nature of the program and integration across UIC and regional BIRCWH Programs; and (4) the use of evidence-based mentoring practices to prepare scholars to conduct team science and address barriers facing new female and URM investigators. Our short-term objectives build upon these strengths through ongoing program activities and several new initiatives. Ongoing activities include: a) supplementing team mentoring programs with new training and tools, b) optimizing existing and new UIC partnerships, and c) augmenting our strong didactic curriculum in women's health research. BIRCWH activities at UIC related to sex and gender influences in health and disease will advance the ORWH goal to accelerate the translation of knowledge into improved health care for women.