ABSTRACT The Councils on Arteriosclerosis, Thrombosis, and Vascular Biology (ATVB) and Peripheral Vascular Disease (PVD) of the American Heart Association (AHA) hold an annual Spring Meeting “Vascular Discovery: From Genes to Medicine” the most recent of which (in-person) was held in Seattle, WA May 12-14, 2022. This first post-pandemic in-person meeting was a resounding success with 507 attendees and 336 abstracts submitted. Feedback from attendees was overwhelmingly positive, with the highest overall satisfaction ratings in 4 years. These encouraging statistics provide tangible evidence of the broad interest and commitment of the scientific community in the topic areas of ATVB, PVD and vascular medicine and the overwhelming enthusiasm for the format and atmosphere of this meeting. Basic scientists, translational researchers and clinicians, seasoned investigators and early career scientists, enjoy coming to this AHA Spring meeting to share and learn cutting-edge vascular science and network with researchers across disciplines. The next Vascular Discovery conference is scheduled to be held May 10-12, 2023 at the Marriott Copley Place in Boston, MA. As with previous applications, this proposal specifically requests support for our Young Investigator Travel Awards. Knowing that early stage investigators are the future of our scientific progress, a major emphasis of our annual conference is to encourage the active involvement of the younger cohort of investigators in the ATVB and PVD Councils of the AHA. This meeting provides early career investigators with ample opportunities to present talks and posters and to participate in extensive career development programming. Our Young Investigator Travel Awards have been supported by the NIH/NHLBI for 16 years. These awards are an integral part of our strategy to recruit, retain and actively engage young investigators in the fields of arteriosclerosis, thrombosis, vascular biology and vascular medicine research that are of major importance to the NIH-NHLBI and the health of the U.S. population.