# The Ohio State University Chronic Pancreatitis Diabetes Pancreas Cancer (CPDPC) Clinical Center

> **NIH NIH U01** · OHIO STATE UNIVERSITY · 2022 · $100,000

## Abstract

ABSTRACT
The mechanistic underpinnings of diseases involving the exocrine pancreas are poorly understood. Chronic
pancreatitis is often accompanied by inflammation of the pancreas, irreversible fibrosis, and destruction of the
pancreatic parenchyma resulting in abdominal pain, malnutrition, exocrine pancreatic insufficiency,
pancreatogenic diabetes, and, in some cases, pancreas cancer. We have developed a network of adult and
pediatric investigators to form The Ohio State University Clinical Center (OSU CC). In a multidisciplinary
collaboration with other clinical centers in the Consortium for the Study of Chronic Pancreatitis, Diabetes, and
Pancreatic Cancer Clinical Centers (CPDPC-CCs) (U01), the OSU CC has helped develop four (4) major
observational studies during the initial funding cycle to address research gaps in our understanding of diseases
of the exocrine pancreas. Specifically, the OSU CC seeks to validate proposed diagnostic biomarkers in
chronic pancreatitis, pancreatogenic diabetes, and pancreas cancer.

## Key facts

- **NIH application ID:** 10684455
- **Project number:** 3U01DK108327-08S1
- **Recipient organization:** OHIO STATE UNIVERSITY
- **Principal Investigator:** DARWIN LEWIS CONWELL
- **Activity code:** U01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $100,000
- **Award type:** 3
- **Project period:** 2015-09-28 → 2025-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10684455

## Citation

> US National Institutes of Health, RePORTER application 10684455, The Ohio State University Chronic Pancreatitis Diabetes Pancreas Cancer (CPDPC) Clinical Center (3U01DK108327-08S1). Retrieved via AI Analytics 2026-05-21 from https://api.ai-analytics.org/grant/nih/10684455. Licensed CC0.

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