# K-CORE: Curation and Knowledge Management for SPARC

> **NIH NIH OT2** · UNIVERSITY OF CALIFORNIA, SAN DIEGO · 2022 · $1,992,079

## Abstract

This proposal outlines plans for the creation of K-CORE, a new core for SPARC that will provide
curation of SPARC datasets, knowledge management and services for the SPARC Knowledge
Graph. The latter is a semantic store that combines information on SPARC datasets annotated
according to the SPARC Minimal Information Standard (MIS) with functional and anatomical
topologically based connectivity knowledge for the autonomic nervous system (ANS). Included in
the ANS are the sympathetic, parasympathetic and enteric nervous systems, with reference to
sensory and motor pathways as necessary. Technology development in SPARC is provided by
the SPARC Data and Resource Center (DRC), currently comprising DAT-CORE, which provisions
the data platform, MAP-CORE, which develops 2 and 3D mapping tools and a map-based GUI,
and SIM-CORE which fields the simulation platform. To date, the curation and knowledge
management functions have been conducted under the purview of MAP-CORE, led by Dr. Peter
Hunter at the Auckland Bioinformatics Institute with a subcontract to UCSD. However, these
services are sufficiently broad and cross cutting that they should be managed through a separate
core. The K-CORE team has been providing curation and knowledge management services for
SPARC since 2018 and thus are deeply familiar with the project.

## Key facts

- **NIH application ID:** 10684487
- **Project number:** 3OT2OD030541-01S2
- **Recipient organization:** UNIVERSITY OF CALIFORNIA, SAN DIEGO
- **Principal Investigator:** MARYANN E MARTONE
- **Activity code:** OT2 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $1,992,079
- **Award type:** 3
- **Project period:** 2020-09-04 → 2023-09-03

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10684487

## Citation

> US National Institutes of Health, RePORTER application 10684487, K-CORE: Curation and Knowledge Management for SPARC (3OT2OD030541-01S2). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10684487. Licensed CC0.

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