# Proteomics

> **NIH NIH P30** · SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · 2023 · $253,525

## Abstract

ABSTRACT – PROTEOMICS SHARED RESOURCE 
The mission of the Proteomics Shared Resource is to provide cost-effective, state-of the-art analytical proteomics 
services to investigators of the Cancer Center. During the past funding period, the Core was upgraded as a result 
of a major initiative by SBP, which provided more than $2.5M in support for the purchase of new equipment. This 
upgraded equipment included two Thermo Fusion Lumos systems, Q-Exactive Plus and TSQ Quantiva systems, 
all with appropriate coupled LC systems. Additionally, there was addition of a Bravo AssayMap automation 
system for sample preparation, and the recruitment of highly trained proteomics scientists—the Core staff now 
includes three Ph.D.-level scientists. The Proteomics Core provides a full array of services, including study 
design, sample preparation, and the generation, analysis, and interpretation of data. In addition to straightforward 
protein identification, the Core supports work involving cutting-edge proteomics methodologies, including labeled 
and label-free quantitative proteomics, and both focused and global post-translational modification (PTM) 
analyses. In the past several years, the Core has additionally taken on larger scale high throughput projects. 
The Core also supports affinity purification coupled to mass spectrometry (APMS) using proximity labeling and 
epitope tagging technologies to study protein–protein interactions. More recently, the Core has worked closely 
with Cancer Center laboratories to implement new proteomics technologies, including histone PTM profiling, 
biomarker discovery in biofluids, and drug target identification. Over the past funding period, the Proteomics 
Core has provided services to 41 Center members representing all three programs, and this work has supported 
at least 43 cancer-relevant publications.

## Key facts

- **NIH application ID:** 10686137
- **Project number:** 5P30CA030199-42
- **Recipient organization:** SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE
- **Principal Investigator:** Maria Teresa Diaz Meco Conde
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2023
- **Award amount:** $253,525
- **Award type:** 5
- **Project period:** 1997-05-01 → 2025-04-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10686137

## Citation

> US National Institutes of Health, RePORTER application 10686137, Proteomics (5P30CA030199-42). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/10686137. Licensed CC0.

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