# Diversity Supplement for Kristina Bell: Biopsychosocial pain predictors of mobility decline in aging

> **NIH NIH R01** · UNIVERSITY OF FLORIDA · 2023 · $18,272

## Abstract

A. Project Summary or Abstract: Mobility disability impacts approximately 30% of individuals aged 60-69, 40%
of individuals aged 70-79, and 55% of individuals age 80 or older. Emerging cross-sectional evidence suggests
that self-reported musculoskeletal pain may be one of the major drivers of age-related mobility decline. Despite
this evidence, significant knowledge gaps remain because the relationships among chronic musculoskeletal
pain, aging, mobility, psychosocial function, and the brain have not been studied longitudinally in the same older
individuals. Our prospective study design will provide novel information on the role of pain-related brain changes
as predictive factors of age-related mobility decline. The proposed work will allow us to determine whether pain
as well as brain structure and function predict mobility decline longitudinally (Aim 1) and whether brain measures
mediate the pain-mobility association prospectively (Aim 2). The proposed work integrates multiple fields of study
within a biopsychosocial approach to study pain and mobility in the older population.

## Key facts

- **NIH application ID:** 10687327
- **Project number:** 3R01AG076082-01A1S1
- **Recipient organization:** UNIVERSITY OF FLORIDA
- **Principal Investigator:** Stephen Coombes
- **Activity code:** R01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2023
- **Award amount:** $18,272
- **Award type:** 3
- **Project period:** 2022-06-01 → 2027-02-28

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10687327

## Citation

> US National Institutes of Health, RePORTER application 10687327, Diversity Supplement for Kristina Bell: Biopsychosocial pain predictors of mobility decline in aging (3R01AG076082-01A1S1). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10687327. Licensed CC0.

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