ABSTRACT – ADMINISTRATIVE CORE The Administrative Core supports the CHIPTS mission by providing scientific guidance, administrative leadership and program evaluation processes and leads all operational, dissemination, and key decision- making functions for the entire center. The Administrative Core develops and implements the strategic plan. It facilitates collaboration and fosters synergy across the cores and CHIPTS affiliated institutions; and it guides CHIPTS' activities in global HIV prevention. The Administrative Core is led by the Senior Leadership Team: Director Steve Shoptaw, PhD; Co-Director Raphael Landovitz, MD, MSc; Executive Director Uyen Kao, MPH. The specific aims are: (1) Science: To provide scientific, programmatic, and administrative leadership to the overall center; promote collaborative and multidisciplinary work among its scientists to advance the center's mission; develop and implement the center's strategic plan; ensure scientific accountability using a continuous quality improvement and evaluation process; and manage center's fiscal resources; (2) Networking: To maintain the center's internal and external communication infrastructure to ensure effective dissemination and sharing of information; coordinate its networking activities to foster synergy across its cores and promote collaborations with other HIV-related centers, institutions, and partners; (3) Capacity Building: To coordinate mentoring and training activities to increase the capacity of investigators, key community partners and stakeholders to implement and scale-up high impact HIV prevention and treatment developments. The Administrative Core monitors and ensures diversity, productivity and culturally competent leadership for all of CHIPTS core directors and co-directors, ultimately measured by significance and innovation in contributions to science, networking and capacity building. It disseminates information, leads interactions, and conducts evaluation and quality improvement activities for the cores and the overall center. It houses all communications between the Senior Leadership Team and therein brokers communication with the community and scientific advisory boards, and the Core Committee, which is comprised of the core directors, co-directors and associate directors from four other CHIPTS cores. Within the Administrative Core is the Global HIV Prevention Program. This global program provides infrastructure support to CHIPTS investigators and their partners at international institutions to create high-impact science agendas, especially in countries that have high HIV prevalence and incidence, especially for populations with mental health and substance use disorders and barriers to social and structural determinants of health that correspond with living with or at risk for HIV.