# Maximizing Use of High-Quality Evidence in Eye Care: Cochrane Eyes and Vision US Project

> **NIH NIH UG1** · UNIVERSITY OF COLORADO DENVER · 2023 · $997,486

## Abstract

PROJECT SUMMARY/ABSTRACT
Vision healthcare should be based on science; in this era of data deluge, evidence-informed practice is needed
more than ever. Cochrane is the only international organization that has as its core mission to synthesize (via
systematic reviews) and keep up to date the world's literature for all of healthcare. Systematic reviews use a
highly structured and reproducible methodology to identify, appraise, and synthesize available evidence for
specific clinical questions. Cochrane Eyes and Vision (CEV) aims to prepare and promote access to
systematic reviews of interventions used to prevent, diagnose, or treat eye conditions and visual impairment.
Since 2002, the CEV US Project (CEV@US) has published 101 systematic review protocols, 104 systematic
reviews, and 75 methodological papers and book chapters; has educated over 100,000 individuals in methods
for systematic reviews; and has informed 121 clinical practice guidelines in the US and internationally. Since its
start, CEV@US has been laying the groundwork for having an impact on practicing clinicians: demonstrating to
all who are interested how to conduct an excellent systematic review (e.g., education, journals, methods
research), how to apply this knowledge (e.g., clinical practice guidelines and decision-support applications),
and forming important partnerships (e.g., with clinicians and patients/consumers).
The current societal priorities and observed vision health disparities suggest an urgent need for evidence on
interventions to reduce vision health inequity among socioeconomically disadvantaged groups. The focus of
our 2022-2027 competitive renewal is impact – impact of CEV reviews on clinical practice, healthcare
equity, and health policy in the US and internationally.
Aim 1: We will prepare systematic reviews that address prioritized questions in collaboration with clinicians
and methodologists, publish the reviews, and regularly update them as new research emerges. We will apply
state-of-art methods in producing these reviews. Aim 2: We will partner with individual (e.g., clinicians,
patients) and organizational stakeholders (e.g., professional societies, academic medical centers, journals) to
ensure that the knowledge underpinning clinical practice and policy is reliable, available, and applied. Aim 3:
We will build research capacity by educating health professionals. Our education is flexible and tailored, and is
offered online and in-person, via professional organizations, clinical programs, and one-time workshops. Aim
4: We will conduct foundational methodological research related to systematic reviews and influence the field
of evidence synthesis. We will evaluate the impact CEV@US activities using a mixed-method study. Aim 5:
We will promote evidence-informed decision making by disseminating the results of our research widely.

## Key facts

- **NIH application ID:** 10690543
- **Project number:** 5UG1EY020522-15
- **Recipient organization:** UNIVERSITY OF COLORADO DENVER
- **Principal Investigator:** Tianjing Li
- **Activity code:** UG1 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2023
- **Award amount:** $997,486
- **Award type:** 5
- **Project period:** 2010-05-01 → 2027-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10690543

## Citation

> US National Institutes of Health, RePORTER application 10690543, Maximizing Use of High-Quality Evidence in Eye Care: Cochrane Eyes and Vision US Project (5UG1EY020522-15). Retrieved via AI Analytics 2026-05-21 from https://api.ai-analytics.org/grant/nih/10690543. Licensed CC0.

---

*[NIH grants dataset](/datasets/nih-grants) · CC0 1.0*