Delaware Center for Neuroscience Research Administrative Core The role of the administrative core will be to coordinate resources, expertise and programs across Delaware State University and the University of Delaware to support the continued success of the Delaware Center for Neuroscience Research. The focus of the Administrative Core is to build and sustain a community of researchers across Delaware who are investigating the dynamic functions of the brain and nervous system, and to grow the number of investigators at our institutions who are competitive for external funding for their research. The Administrative Core is centered at Delaware State University with a subcore at the University of Delaware to ensure coordination of efforts at both institutions. The Administrative Core will provide the oversight necessary for continued success of the Delaware Center for Neuroscience Research during COBRE Phase III and then to ensure the long-term sustainability of the Center beyond the Phase III award. The Center Director, Dr. Melissa Harrington, will continue to lead the Administrative Core and Dr. Jeffrey Rosen will initially continue to act as the director for the University of Delaware. Dr. Anna Klintsova, an R01-funded graduate of our Phase I COBRE award will be joining the leadership team as a co-director for the UD subcore. This addition is part of succession planning for the project as Dr. Rosen will retire during the term of the Phase III award. An internal advisory committee of graduated investigators from earlier phases of the Center and veteran research core directors will help guide the investigator development plan and maturation of the cores toward long term sustainability Our Neuroscience Center brings together a multidisciplinary group of neuroscientists at DSU and the University of Delaware to take part in Center-sponsored meetings, retreats, symposia and professional development activities. The administrative core personnel, the PI, the UD Director and co-director, and the Program Coordinator, with the assistance of the Internal Advisory Committee will coordinate and oversee the annual symposium, mock study sections, the research retreats and other professional development activities of the Center. The PI and the administrative core will be responsible for evaluating the performance of Center constituents, including the performance of the cores, the productivity of the pilot investigators and the overall impact of the Center. The Admin Core will also be responsible for annual reporting to NIGMS and to various internal constituencies. In addition, as NIGMS has increased its investments in IDeA programs through administrative supplements applications for supplemental funding are of increasing importance. In phase III the Admin Core will also have a focus on ensuring that Neuroscience Center teams submit applications for all of the administrative supplements for which we are eligible.