# Core 3. Immunology and Pathology.

> **NIH NIH U19** · LAWRENCE LIVERMORE NATIONAL SECURITY, LLC · 2023 · $471,359

## Abstract

SUMMARY/ABSTRACT
CORE 3: IMMUNOLOGY AND PATHOLOGY
Dr. Rasley (PI) and Dr. Weilhammer (Co-I) will establish and operate an Immunology and Pathology Core that
serves the Cooperative Research Center for Nano-Scaffold Vaccines Against Chlamydia trachomatis (Ct) by
providing facilities, expertise, effort, materials, and information management that helps achieve the aims of all
three research projects. We have the established laboratory facilities, instrumentation, and storage necessary
for all immunological assays that will be performed as part of this Core, as well as access to a state-of-the-art
animal AAALAC accredited animal facility. We will establish and maintain standard operating procedures and
training materials sufficient to develop the personnel with the expertise necessary to reproducibly perform
procedures needed to support the immunological analyses needed by the individual projects. The Immunology
and Pathology Core will be staffed to provide the effort required for all animal studies and subsequent
immunologic analyses as well as properly acquiring and processing samples that will be sent offsite for analyses
(pathology; UC Davis). The core will be highly centralized with personnel and facilities at Lawrence Livermore
National Laboratory (LLNL), with the exception of the pathology analyses which will be performed at UC
Davis. The Immunology and Pathology Core can also work as a user facility, providing training and access to
facilities that might enable research and development for the individual projects that do not have the expertise
or equipment at their locations. The core will also compile all data generated for each Project and provide a
comprehensive report to the Project PIs. Using a platform such as Box, we envision data from the Cores be
available to all team ambers at any given time in order to facilitate cross fertilization of ideas.

## Key facts

- **NIH application ID:** 10694899
- **Project number:** 5U19AI144184-05
- **Recipient organization:** LAWRENCE LIVERMORE NATIONAL SECURITY, LLC
- **Principal Investigator:** Amy Rasley
- **Activity code:** U19 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2023
- **Award amount:** $471,359
- **Award type:** 5
- **Project period:** 2019-08-08 → 2025-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10694899

## Citation

> US National Institutes of Health, RePORTER application 10694899, Core 3. Immunology and Pathology. (5U19AI144184-05). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/10694899. Licensed CC0.

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