PROJECT SUMMARY/ABSTRACT Adverse pregnancy outcomes and complications such as preterm birth, preeclampsia, intrauterine growth restriction, and gestational diabetes present significant risks to pregnant people. The nuMoM2b Heart Health Study (nuMoM2b-HHS2) determines the cardiovascular and cerebrovascular health impact of such adverse pregnancy outcomes through following nearly 7,000 people from first pregnancy through 8-16 years post-partum. The nuMoM2b-HHS2 work has helped increase understanding of high blood pressure indicators, impact of exercise, sleep disorders, neighborhood characteristics, stress and depression, SES factors and biological influences on future health and disease. We propose to support 2-3 early career investigator scholars with meritorious proposals for additional analyses of the data. Using a similar approach in the past, early-career investigator scholars, through a competitive and peer-reviewed process, had projects selected for internal support. This led to two obstetricians, one cardiologist, and one neurologist being newly integrated as active participants in the nuMoM2b-HHS2 network, as well as papers that were published in peer-reviewed journals. These future 2-3 awards will require administrative and technical support for the scholar, as well as the analysis of data generated, which will be completed by the nuMoM2b-HHS2 team at RTI. For the nuMoM2b-HHS2 network, this proposal aligns well with the Trans-NIH Strategic Plan for Women’s Health Research, particularly Goal 4: Promote Training and Careers to develop a well-trained, diverse, and robust workforce to advance science for the health of women. The nuMoM2b-HHS2 team would value the opportunity to support additional scholars this year, continuing to maintain a strong focus on diversity. RTI will provide an ideal setting for support of young investigators from various disciplines to engage them in this unique area of science and promote strong collaborations that will propel the science forward.