# Patient-Reported Outcomes for Acute Asthma Care and Treatment (PROAACT)

> **NIH NIH K23** · STANFORD UNIVERSITY · 2023 · $191,630

## Abstract

PROJECT SUMMARY/ ABSTRACT
This K23 award will enable the candidate, Michelle Lin, MD, MPH, MS, to become an
independent physician scientist focused on improving patient-reported outcomes for emergency
department (ED) care of asthma and other acute cardiopulmonary conditions. Asthma affects 1
in every 12 persons in the U.S., resulting in 1.9 million ED visits annually; however, the impact
of ED care on patient-reported outcomes after acute exacerbations is unknown—a gap which
limits the evaluation of interventions to improve ED asthma care. In her pilot work, Dr. Lin has
identified candidate items and scales for the novel Patient-Reported Outcomes for Acute
Asthma Care and Treatment (PROAACT) instrument. During this K23, Dr. Lin will 1) evaluate
the validity and reliability of the PROAACT instrument; 2) test whether receiving more guideline-
concordant ED care is associated with improved PROAACT responses; and 3) evaluate the
association between PROAACT scores and subsequent ED revisits and hospitalizations, which
will inform the inclusion of PROAACT and other candidate predictors in future risk adjustment
models. To achieve these aims, this proposal includes an integrated curriculum consisting of
intensive mentorship and didactic coursework in patient-centered research, instrument
development and validation including psychometric methods, clinical data management, and
novel approaches to outcome measurement applying geospatial techniques to incorporate
social and environmental data known to differentially affect asthma and health outcomes. Dr.
Lin’s career development and training activities also include building a research network of
peers and collaborators, engaging with asthma patients in local communities, and participating
in national scientific meetings. Dr. Lin has assembled a mentorship team of national leaders
with expertise in patient-oriented asthma and emergency medicine research, patient-centered
outcomes research, instrument development, health care quality measurement, and outcome
assessment. The proposed research and didactic plan will allow Dr. Lin to develop expertise in
patient-reported outcome performance measure development, become a leader in patient-
centered asthma and emergency care research, and enable Dr. Lin's transition to an
independent clinical investigator focused on developing, measuring and improving patient-
reported outcomes for asthma and other cardiopulmonary conditions. Completion of this project
will result in a novel PROM for adult ED asthma patients, advance the understanding of how ED
care impacts patient-reported outcomes, and enable interventions to improve outcomes that
matter to ED patients with asthma.

## Key facts

- **NIH application ID:** 10697388
- **Project number:** 5K23HL143042-05
- **Recipient organization:** STANFORD UNIVERSITY
- **Principal Investigator:** Michelle P Lin
- **Activity code:** K23 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2023
- **Award amount:** $191,630
- **Award type:** 5
- **Project period:** 2019-08-15 → 2024-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10697388

## Citation

> US National Institutes of Health, RePORTER application 10697388, Patient-Reported Outcomes for Acute Asthma Care and Treatment (PROAACT) (5K23HL143042-05). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/10697388. Licensed CC0.

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