Extraordinary Dispersion Engineering In Enabling Ultrafast Swept Source visiblelight Optical Coherence Tomography

NIH RePORTER · NIH · R43 · $253,012 · view on reporter.nih.gov ↗

Abstract

Project Summary This SBIR Phase 1 project focuses on developing, characterizing, and validating a new swept-source laser system to enable the next-generation clinical visible-light optical coherence tomography (vis-OCT). We will develop a novel design of photonic bandgap fiber that comprises Fiber Bragg Grating array to temporally disperse broadband picosecond-pulses to create a wavelength sweeping pulse train. The new swept source can operate up to tens of MHz frequencies without mechanical moving parts, enabling ultra-high-speed swept-source vis-OCT (SS-vis-OCT) for the first time. The new light source will also enable truly shot-noise-limited performance in vis-OCT while mitigating the artifacts caused by both eye motions and fringe washout. During the project period, we will design, fabricate, and optimize the new swept-source laser to achieve the desired sweeping frequency, bandwidth, and phase stability. We will further develop a prototype SS-vis-OCT and fully test its performance in phantom eyeballs, ex vivo bovine eyes, and blood vessel phantoms.

Key facts

NIH application ID
10698705
Project number
1R43EY034800-01A1
Recipient
OPTICENT, INC.
Principal Investigator
Roman Kuranov
Activity code
R43
Funding institute
NIH
Fiscal year
2023
Award amount
$253,012
Award type
1
Project period
2023-06-01 → 2024-05-31