# PDB MANAGEMENT BY THE RESEARCH COLLABORATORY FOR STRUCTURAL BIOINFORMATICS

> **NIH NIH R01** · RUTGERS, THE STATE UNIV OF N.J. · 2022 · $800,000

## Abstract

Administrative Supplement Request in Response to PA-20-272
Parent Award Identifier: 1R01GM133198
Parent Award Title: PDB Management by the Research Collaboratory for Structural Bioinformatics
Parent Award Principal Investigator: Stephen K. Burley, M.D., D.Phil.
Supplement Request: Scaling of RCSB PDB Backend and Frontend Services for RCSB.org
Project Summary/Abstract:
In its role as a core NIH data repository, the Research Collaboratory for Structural Bioinformatics Protein Data
Bank (RCSB PDB) is committed to the best practices articulated by the FAIR and TRUST principles. Established
in 1971 as the first open-access digital data repository in biology, the PDB has been a leading exemplar of FAIR
and a pioneer in the open access movement. RCSB PDB was an early adopter in securing CoreTrustSeal
certification and advocating publicly for the TRUST principles. In this supplement application, funds are
requested to support scaling of RCSB PDB research-focused RCSB.org web portal Backend and
Frontend Services by two orders of magnitude for delivery of ~200 million Computed Structure Models
(CSMs) from AlphaFoldDB and the ModelArchive alongside all of the experimentally-determined structures
stored in the PDB. Parallel delivery of CSMs with PDB data will enable many millions of RCSB.org users
worldwide to analyze, visualize, and explore predicted 3D structural models for nearly every protein
represented within UniProt (fully integrated with ~200,000 PDB structures).

## Key facts

- **NIH application ID:** 10702253
- **Project number:** 3R01GM133198-04S1
- **Recipient organization:** RUTGERS, THE STATE UNIV OF N.J.
- **Principal Investigator:** STEPHEN K BURLEY
- **Activity code:** R01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $800,000
- **Award type:** 3
- **Project period:** 2019-08-01 → 2024-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10702253

## Citation

> US National Institutes of Health, RePORTER application 10702253, PDB MANAGEMENT BY THE RESEARCH COLLABORATORY FOR STRUCTURAL BIOINFORMATICS (3R01GM133198-04S1). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10702253. Licensed CC0.

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