PROJECT SUMMARY This application is our vision for the "Atlanta Network for Iraining !n KUH .§.cientific Research (ATLANTIS)". Our goal is to create a city-wide resource for training the next generation of researchers studying KUH-related diseases. Emory will engage two of its close academic partners in metropolitan Atlanta, Morehouse School of Medicine (MSM) and Georgia Institute of Technology (GaTech), to create a strategic multi-institutional alliance designated to promote and foster KUH research training. ATLANTIS will establish new and strengthen existing collaborative research networks, research training programs, and career development opportunities that will foster a sustained interest in KUH diseases, thereby increasing the pipeline of these scientists into the biomedical workforce. Our goals are: 1) provide the intellectual and research platform to attract and train the next generation of new basic and clinical scientists in KUH research; 2) promote impactful interdisciplinary and multi-institutional collaborations with the shared objective of KUH-related human disease investigation; 3) promote KUH biomedical investigator success by enhancing the career development of young scientists; 4) increase research and teaching collaborations in Atlanta by promoting interactions between Emory, GaTech, MSM, and Spelman College, Morehouse Colleges and Clark Atlanta University (Historically Black Colleges and Universities (HBCUs); and 5) increase the number of well-qualified underrepresented minority (URM) students entering competitive careers in biomedical research. Aim 1 will develop an integrated, city-wide Training Network for KUH research training (TL1 Training Core). Pre- and post-doctoral trainees will perform original KUH research under the mentorship of a scientifically diverse preceptor pool. ATLANTIS will create a vibrant, supportive and dynamic training environment to encourage trainees to answer important questions that directly affect human health and disease. This rich experience will promote KUH research and prepare trainees for their future research. Aim 2 will develop a dynamic Networked Program actively engaging TL1 and other KUH trainees through peer networking, team science, and outreach efforts in KUH research (Network Core). We will implement a cloud-based community software platform, ATLANTIS-Connect, explicitly designed to foster, support, and supplement traditional in-person interactions and engage trainees at all career stages, promote interest in KUH research, and develop peer-networking and peer-to-peer mentoring. Aim 3 will develop an integrated Professional Development program that enhances trainee and preceptor professional development (Professional Development Core). Trainees will participate in professional development opportunities offered by the Office of Postdoctoral Education and the graduate programs at Emory (Laney Graduate School), GaTech, and MSM. Our goal is to provide a meaningful research experience coup...