# ChimeraX -- Next Generation Visualization and Analysis Software for Multiscale Modeling

> **NIH NIH R01** · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · 2023 · $664,692

## Abstract

PROJECT SUMMARY/ABSTRACT
The goal of this project is to enable scientific discovery and advances in biomedical research through
the development of cutting-edge software tools that provide integrated visualizations and analyses of
molecular structures and related biological information. Our tools can be applied to diverse types of
biomolecular data, including atomic-resolution coordinates, 3D cryo-EM density maps, and protein
and nucleic acid sequences, annotations, and networks. We focus on unmet software needs for basic
and applied biomedical research using highly trained and talented staff, with excellent interdisciplinary
knowledge and specialized, state-of-the-art expertise in software engineering, computer graphics
visualization, and data analysis. Our primary efforts are in the interactive visualization and analysis of
structures of molecules, molecular assemblies, and protein sequence-structure relationships. These
areas are critical for addressing important and highly relevant biomedical problems such as
identifying the molecular bases of disease, identifying targets for drug development, designing drugs,
and engineering proteins with new functions. Our software tools enable scientists to understand,
analyze, and illustrate to others the important principles of molecular structure, function, and
interactions. These tools are widely recognized as works of the highest quality, and are available for
free on our website in binary and source-code form. We support and maintain these tools, and
provide detailed documentation and tutorials. Our technological developments are disseminated
widely via scientific publications, lectures, software distribution, and video animations.

## Key facts

- **NIH application ID:** 10707058
- **Project number:** 5R01GM129325-06
- **Recipient organization:** UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
- **Principal Investigator:** THOMAS E FERRIN
- **Activity code:** R01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2023
- **Award amount:** $664,692
- **Award type:** 5
- **Project period:** 2018-07-01 → 2026-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10707058

## Citation

> US National Institutes of Health, RePORTER application 10707058, ChimeraX -- Next Generation Visualization and Analysis Software for Multiscale Modeling (5R01GM129325-06). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10707058. Licensed CC0.

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