# Translational Research in Alzheimer's Disease and related Dementias (TRADD)

> **NIH NIH T32** · UNIVERSITY OF ARIZONA · 2023 · $294,459

## Abstract

Project Summary/Abstract
The University of Arizona (UArizona) Training Program to Advance Translational Research on Alzheimer's
Disease and AD Related Dementias (AZ-TRADD) is designed to address knowledge and experience gaps in AD
therapeutic discovery and preclinical translational development. To meet this challenge, the UArizona
Translational Research in AD and related Dementias (AZ-TRADD) training program is designed as a problem
based translational learning experience for predoctoral Ph.D and M.D./Ph.D fellows. In alignment with the 2021
NIH Alzheimer’s Research Summit: Path to Precision Medicine for Treatment and Prevention and the 2011
National Alzheimer’s Project Act (NAPA), the goal of the AZ-TRADD training program is to fill critical gaps that
exist for AD translational research in academic graduate programs. To achieve this goal, the AZ-TRADD program
will: 1) recruit trainees across multiple scientific disciplines; 2) employ problem-based learning approaches to
solve challenges in AD therapeutic development with emerging tools and techniques; and 3) equip AZ-TRADD
trainees with career development and leadership skills necessary to conduct team science and manage
multidisciplinary teams. Through this approach, we ensure that AZ-TRADD trainees develop deep translational
research expertise necessary for AD therapeutic development, while: 1) cultivating the ability to creatively and
collaboratively solve problems working with experts across the translational landscape as part of large-scale
team science; 2) gaining an applied understanding of how data science, particularly using data generated by
AMP-AD, M2OVE-AD and ADNI, can accelerate translational research and provide avenues to novel therapeutic
insights; 3) connecting geno- and phenotypic variations and multifaceted etiology of AD to therapeutic targets;
and 4) gaining essential professional and business skills to navigate a diverse funding landscape and translate
discoveries into the clinical setting. AZ-TRADD fellows will receive career mentoring and leadership development
skills to manage multi-disciplinary teams in the 21st century that is Patient Inspired and Data Driven. The AZ-
TRADD training program will develop a diverse, cross-disciplinary, and translationally oriented workforce to meet
the critical challenge of creating a workforce capable of advancing therapeutics to prevent, delay, and treat AD
and AD related dementias.

## Key facts

- **NIH application ID:** 10709167
- **Project number:** 1T32AG082631-01
- **Recipient organization:** UNIVERSITY OF ARIZONA
- **Principal Investigator:** ROBERTA EILEEN BRINTON
- **Activity code:** T32 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2023
- **Award amount:** $294,459
- **Award type:** 1
- **Project period:** 2023-09-01 → 2028-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10709167

## Citation

> US National Institutes of Health, RePORTER application 10709167, Translational Research in Alzheimer's Disease and related Dementias (TRADD) (1T32AG082631-01). Retrieved via AI Analytics 2026-05-21 from https://api.ai-analytics.org/grant/nih/10709167. Licensed CC0.

---

*[NIH grants dataset](/datasets/nih-grants) · CC0 1.0*