Leadership Administrative Core SUMMARY The objective of the Leadership Administrative Core is to promote the greatest scientific productivity and educational value by effective management of SCORE resources. The Core will be led by Karen Reue, PhD, who will work closely with all project and core leaders, as well as the local Scientific Advisory Committee and External Advisors, to promote an integrated approach to better understand the role of biological sex as a determinant of risk, development and treatment of cardiometabolic diseases. The aims are as follows: Aim 1: Provide overall scientific leadership of the SCORE Aim 2: Ensure effective and efficient administrative management of SCORE resources Aim 3: Organize an annual Symposium on sex differences and meeting with advisors Aim 4: To foster collaboration with other SCORE programs and UCLA Women’s Health Organizations Overall, the Administrative Core will serve a critical coordinating role for all components to promote the most administratively efficient, and most scientifically productive, program.