ABSTRACT The Leadership and Administrative Core (LAC) will provide administrative and intellectual leadership to implement the theme of the San Diego Alzheimer’s Disease Resource Center for Minority Aging Research (SD AD-RCMAR) to address Alzheimer’s Disease and Related Dementias (ADRD) inequities through novel research targeting multilevel factors to inform interventions focused on Hispanic/Latino, limited English proficient (LEP) and refugee communities. The LAC will also coordinate the proposed training activities, and communications and activities between the PIs, the Core Leaders and Core Members, the AD-RCMAR Scientists and their mentors. It will promote and support the integration of Diversity, Equity, Inclusion and Accessibility (DEIA) in all activities of the Center. The LAC will have four components to assist in accomplishing the Specific Aims, including a Center Administrative Unit, Executive Committee, Pilot Project Review Panel and External Advisory Committee. These components have both unique and complementary functions to ensure the center operates effectively and efficiently. Further, the LAC will connect with the larger UC San Diego (UCSD) and San Diego State University (SDSU) research communities to leverage the existing infrastructure and collaborations between the SD AD-RCMAR, these research communities, and other NIH/NIA-supported programs. The result will be a true multi-disciplinary partnership between UCSD, one of the nation’s leading research institutions (UCSD) and SDSU, a research-prolific Hispanic Serving Institution.