# Yale Clinical and Translational Science Award: Nwanaji-Enwerem Diversity in Health Related Research

> **NIH NIH UL1** · YALE UNIVERSITY · 2023 · $209,852

## Abstract

SUMMARY: Uzoji Nwanaji-Enwerem
The Parent Award: The Yale Center for Clinical Investigation (YCCI) was established in 2005 to develop
institutional infrastructure that would better support translational and clinical research and to mentor the next
generation of investigators. The YCCI was awarded the Clinical and Translational Science Award (CTSA) in
2006, now funded by the National Center for Advancing Translational Sciences (NCATS). Since then, the CTSA
has be successfully renewed for Yale three times. The YCCI leverages this funding to provide essential
resources and training to early investigators embarking on careers in translational and clinical research, including
bioinformatic and computational research infrastructure, state-of-the-art research cores, pilot grants, study
design support, administrative and regulatory support, and educational offerings. This funding has gone a long
way, leading to successful mentorship of numerous junior investigators during the most critical phase of their
careers. Since 2006, 161 past or current Junior Faculty Scholars have received more than $700 million in
independent grants (~76% from NIH), producing ~6,300 publications, with 99% of Scholars remaining in clinical
research.
The Candidate: Ms. Uzoji Nwanaji-Enwerem is a PhD Candidate in the Yale School of Nursing, and her long-
term career goal is to become an independent and productive nurse scientist, with a focus on conducting
interdisciplinary research to understand the relationship between psychosocial factors, particularly stigma and
discrimination, with sleep among persons from underrepresented backgrounds.
The Project: Although only representing only 12% of the U.S. population, Black people account for as much
43% of people living with HIV disease. One major challenge is intersectional stigma (stigma related to race,
sexuality, and HIV status), which often is a major contributor to experienced trauma in in these individuals. These
traumatic experiences are associated with physical, mental, emotional, and behavioral health outcomes. The co-
occurrence pattern of trauma and poor sleep among Black PLWH highlights an opportunity to improve health
and quality of life through interventions that address both issues. Accelerated Resolution Therapy (ART) serves
as a brief, cost-effective, and evidence-based treatment for combatting psychological trauma.
Relationship to the Parent Grant: Ms. Nwanaji-Enwerem's research study directly advances the YCCI CTSA's
T3 translational research aim for implementation of health care practices, particularly those that serve under-
represented communities with respect to the management of back people living with HIV. During the award
period, she will receive research mentorship from Dr. LaRon Nelson who has successfully mentored 10 trainees,
9 of which are now funded as independent faculty in tenure-track roles at their respective institutions. She will
also receive research mentorship from Dr. Theddeus Iheanacho who is ...

## Key facts

- **NIH application ID:** 10733278
- **Project number:** 3UL1TR001863-08S1
- **Recipient organization:** YALE UNIVERSITY
- **Principal Investigator:** John H. Krystal
- **Activity code:** UL1 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2023
- **Award amount:** $209,852
- **Award type:** 3
- **Project period:** 2016-07-01 → 2026-05-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10733278

## Citation

> US National Institutes of Health, RePORTER application 10733278, Yale Clinical and Translational Science Award: Nwanaji-Enwerem Diversity in Health Related Research (3UL1TR001863-08S1). Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/grant/nih/10733278. Licensed CC0.

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