# C2-Scientific Core

> **NIH NIH P50** · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · 2024 · $351,898

## Abstract

The long-term goal of the New Mexico Alcohol Research Center is to increase understanding of mechanisms
underlying the effect of prenatal alcohol exposure (PAE) on brain development and to develop novel diagnostic
and therapeutic interventions for Fetal Alcohol Spectrum Disorders (FASDs). The Scientific Core will support
these goals by being a shared research resource that provides investigators with services, expertise and training
that will support, enhance and integrate human and animal studies. Specifically, the Scientific Core will support
the recruitment of human subjects for research components and future pilots via the Neurodiagnostic Clinic
(Center for Developmental Disability (CDD)-Department of Pediatrics). This will ensure that clinical projects
focused on Fetal Alcohol Spectrum Disorders have access to appropriate subject populations. The Scientific
Core will also consolidate and standardize prenatal and postnatal alcohol exposure procedures and mouse
colony management for preclinical components. In addition to reducing research costs, this will allow
investigators to query relationships between their findings and those obtained in other research components
and, thus, facilitate integration of the research components. The Scientific Core will provide research support to
all Components and Pilot Projects in several ways including providing bio-statistics support for all of the research
components, as well as assisting with study design and data analysis to ensure both rigor and reproducibility of
results and consistency in approach across projects where appropriate. The Scientific Core will facilitate the use
of the Center for Brain Recovery & Repair Pre-Clinical Core for studies proposed in several Center components
(e.g., automated behavioral testing, slide scanner, Imaris image analysis software). The Scientific Core will also
support development of new research directions by assisting investigators with implementation of novel
behavioral and alcohol exposure paradigms (including pilot projects). Besides reducing research costs, the
centralized services of the Core will allow investigators to query relationships between their findings and those
obtained in other research components and, thus, facilitate integration of the NMARC’s research components.

## Key facts

- **NIH application ID:** 10741688
- **Project number:** 2P50AA022534-11
- **Recipient organization:** UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR
- **Principal Investigator:** Jonathan L Brigman
- **Activity code:** P50 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $351,898
- **Award type:** 2
- **Project period:** 2014-08-05 → 2029-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10741688

## Citation

> US National Institutes of Health, RePORTER application 10741688, C2-Scientific Core (2P50AA022534-11). Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/grant/nih/10741688. Licensed CC0.

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