# UCLA AIDS Prevention and Treatment Clinical Trials Unit

> **NIH NIH UM1** · UNIVERSITY OF CALIFORNIA LOS ANGELES · 2024 · $3,954,316

## Abstract

Project Summary
The overarching goal of the UCLA AIDS Prevention and Treatment Clinical Trials Unit (CTU) is to make
significant contributions to the development and conduct of HIV treatment and prevention clinical studies in the
context of the DAIDS-sponsored HIV Clinical Research Networks. The UCLA AIDS Prevention and Treatment
Clinical Trials Unit (UCLA APT CTU) is a multidisciplinary research group composed of a core administrative unit
and three clinical research sites (CRSs) in metropolitan Los Angeles, California, one CRS in Southern Brazil and
a new CRS proposed in Buenos Aires, Argentina. We have over 25 years of leadership experience in the design,
implementation, and conduct of clinical trials evaluating both therapeutic and prevention strategies in diverse
populations across all age groups. Under the leadership of the multiple PIs, Judith Currier MD, MSc and Raphael
J. Landovitz, MD, MSc, an experienced multidisciplinary investigator team including Eric Daar, MD, Steve
Shoptaw, PhD, Breno Santos, MD, and Pedro Cahn, MD, PhD together with a group of early midcareer
investigators, Kara Chew, MD, MSc, Jesse Clark, MD, MSc, and Omar Sued, MD, PhD, we will participate in the
design and conduct of studies addressing the highest priority areas for Adult Therapeutics for HIV/AIDS, HIV
Prevention, and HIV Vaccines. The CTU has an administrative core and CRS at the UCLA CARE Center and
additional CRSs at Harbor-UCLA Medical Center, UCLA Vine Street Clinic, and at Grupo Hospitalar Conceição
in Porto Alegre Brazil and at Fundación Huésped (FH), in Buenos Aires, Argentina. We have integrated our
activities across adult medicine and between treatment and prevention to allow for an efficient and collaborative
approach to addressing the highest priority research questions in HIV/AIDS. The CTU provides a gateway for
the contributions of a cadre of outstanding established and emerging investigators at UCLA and from South
America to contribute to clinical trials in HIV/AIDS. We place special emphasis on the recruitment of women and
minorities in all aspects of our work. Shared resources for laboratory specimen processing and storage,
regulatory management, community outreach, recruitment, and education, community advisory board (CAB)
interactions across the Los Angeles-based sites promotes significant CTU-wide efficiency.
Relevance
The clinical research trials conducted by the UCLA AIDS Prevention Clinical Trials unit will have a direct
beneficial effect on the health of millions of people worldwide who are living with or at risk for HIV, tuberculosis
and hepatitis B, transforming the health of people with these infections and preventing new infections. The
research conducted by the CTU will lead to significantly reducing morbidity and mortality, particularly among
populations disproportionately affected by HIV/AIDS.

## Key facts

- **NIH application ID:** 10745294
- **Project number:** 5UM1AI069424-18
- **Recipient organization:** UNIVERSITY OF CALIFORNIA LOS ANGELES
- **Principal Investigator:** Judith S. Currier
- **Activity code:** UM1 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $3,954,316
- **Award type:** 5
- **Project period:** 2007-02-01 → 2027-11-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10745294

## Citation

> US National Institutes of Health, RePORTER application 10745294, UCLA AIDS Prevention and Treatment Clinical Trials Unit (5UM1AI069424-18). Retrieved via AI Analytics 2026-05-21 from https://api.ai-analytics.org/grant/nih/10745294. Licensed CC0.

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