SUMMARY (Administrative core) The Administrative Core of the San Antonio-based Collaborative Research Center on Coccidioidomycosis (SA-CCRC) will provide essential management and supervision of the entire range of the Center’s highly multidisciplinary activities to ensure that our specific aims and component plans are implemented effectively and efficiently. In this core, we outline a management, coordination and integration framework for the scientific, logistical, financial, evaluative, and compliance oversight requirements and resource allocation for the cores and individual research projects. The ultimate goal of this administrative core is to maximize the impact of overall research activities across the entire SA-CRCC. Within this Administrative Core, we have designed a framework for assessing the proposed activities of each Core such that we can ensure progress towards meeting our stated goals. SA-CCRC is designed specifically to have well-coordinated research that can maximize and leverage resources at each of the participating institutions. In addition, the Administrative Core will manage the Development and Research Program (DRP) for pilot funding and mentoring of junior investigators as well as researchers new to the field of coccidioidomycosis research. We propose the following specific aims around which we have designed our management processes: Aim 1. To provide scientific and programmatic leadership, administrative support, and fiscal oversight of the San Antonio- based Collaborative Research Center on Coccidioidomycosis. Aim 2. To establish and manage an effective Development and Research Program (DRP) for pilot funding and mentoring of junior investigators and those new to the coccidioidomycosis field. In summary, through the Administrative Core we will ensure successful achievement of our program mission by serving as the central hub responsible for overall program management, resource allocation, logistical planning, coordination, and oversight of the San Antonio Collaborative Research Center on coccidioidomycosis. The administrative activities within this core are complemented by a robust mentoring and professional development program aimed at preparing the next generation of independent scientists in the field of coccidioidomycosis research.