ABSTRACT The purpose of this application is to request financial support for Cytokines 2023: 11th Annual Meeting of the International Cytokine & Interferon Society (ICIS), October,15-18, 2023, with llivestream and on-demand virtual access through October 29, 2023. This Annual Meeting helps bridge the gap between the scientists performing basic research on molecular and cellular mechanisms of immune cell activation and function with those working to develop this knowledge into novel therapies. The 11th edition comes at a time when cytokine biology, cytokine biomarkers and cytokine therapeutics are revolutionizing modern medicine, providing novel treatments for a wide variety of diseases ranging from lethal inflammatory, autoimmune and allergic diseases, to viral infections and cancer. This year’s theme is “Cytokines and interferons in the precision medicine era”, focusing on the latest developments on cytokine biology in relation to immune regulation, host damage and disease, and the latest progress on cytokines/cytokine inhibitors as novel therapeutics in the clinic. A variety of topics will be covered by leaders in the field in the plenary and parallel sessions such as innate immunity and host defense, adaptive immunity, cytokines in T and B cell responses to vaccination, in Long COVID, HIV and novel targeted therapies from cancer immunotherapy to novel therapeutics in autoimmunity. Since a major goal of the meeting is to promote interactions between scientists and clinicians working in basic, translational or applied research, ample opportunity will be given to poster networking sessions to present the latest advances elated to cytokine research, biomarkers and therapeutics. Greater understanding of mechanisms of disease and novel concepts for therapy have and will continue to emerge from interdisciplinary gatherings where advances can be presented and discussed by established and trainee scientists. The meeting will focus on cytokines in personalized medicine and will provide an opportunity for updates on the development of novel therapeutic interventions in these fields and help spur international collaborations among the meeting participants. Although meeting participants will have primary interests in infectious diseases, cancer and immune-mediated diseases, the program integrates speakers on the periphery of Cytokine and Interferon research to help bridge these disciplines. This interdisciplinary environment is particularly interesting for early career researchers who are not only focused on their own field of research but are beginning to think about the wider implications of their work. Our goal is to increase attendance of early career investigators and trainees and also to achieve higher representation of underrepresented minorities at all levels of career development. Online presentations will consist of livestreamed video presentations for all speakers who give their permission to be recorded, to benefit virtual attendees as well as ...