Project Summary/Abstract: Administrative Core The Administrative Core of the Indiana Alcohol Research Center (IARC) provides leadership by coordinating and optimizing the synergy of the interacting components and cores. The Administrative Core also provides financial oversight and administrative support, and satisfies the critical need for the central management of a complex budget spanning two schools at Indiana University (Medicine at IU and Science at IUPUI), their different departments, and collaborations between Indiana University and Purdue University. The objective and long-term goal of the Administrative Core is the smooth financial management of the grant budget as proposed in this application, in addition to the coordination and integration of the scientific activities of the participants and our collaborators. The rationale for including administrative support from Dr. Kareken’s office in the Department of Neurology is to link the activities of the Center with the broader resources of Research Administration and financial management support from Neuroscience Administration (program manager Tyler Childress), where Neurology resides. The expected outcomes of the activities of this Core are the continued excellence of the science and the coordinated, thematic, and collaborative activities of the Center. The aims of the Administrative Core are therefore to: (1) Provide the scientific leadership, administrative support, and ongoing annual financial oversight for the Indiana Alcohol Research Center. (2) (a) Assist in the identification, recruitment, and development of new investigators in alcohol-related research, b) aid new investigators and their applications for grants, c) help facilitate medical and graduate student exposure to alcohol research, and d) maintain oversight of the web site to serve as a source of information for alcohol researchers, patients and practitioners, and as a link to the Information Dissemination Core. (3) Provide leadership in organizing seminars, conferences, and workshops, and in the dissemination of new research findings to the academic and lay communities. (4) Foster collaborative research ventures between the IARC, other ARCs, and other investigators both domestically and abroad.