# A Self-Guided Mobile Intervention for Adults with Binge Eating and Obesity

> **NIH NIH R41** · OUI THERAPEUTICS, INC · 2023 · $375,273

## Abstract

ABSTRACT
Obesity and comorbid binge eating are serious health problems for more than 40% of adults across the US.7
Health complications due to obesity comprise more than 20% of the nation’s healthcare budget, and the
healthcare costs of individuals with binge eating are $18,152 higher than in obese peers without binge eating.13
The prevalence of binge eating and the substantial burden of healthcare costs highlight the need for treatments
that eliminate binge eating and produce weight loss. Despite this, there is a paucity of interventions that
address these comorbid conditions. In this Phase 1 project, we seek to build a digital therapeutic (called
OTX-401) that will be ready for testing in a large, multi-site, well-powered clinical trial during Phase 2. Positive
results will be the critical initial step to facilitating the widespread implementation and commercialization of the
digital therapeutic to enhance access to highly personalized obesity and binge eating intervention.

## Key facts

- **NIH application ID:** 10761112
- **Project number:** 1R41MH134704-01
- **Recipient organization:** OUI THERAPEUTICS, INC
- **Principal Investigator:** Seth Feuerstein
- **Activity code:** R41 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2023
- **Award amount:** $375,273
- **Award type:** 1
- **Project period:** 2023-09-01 → 2025-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10761112

## Citation

> US National Institutes of Health, RePORTER application 10761112, A Self-Guided Mobile Intervention for Adults with Binge Eating and Obesity (1R41MH134704-01). Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/grant/nih/10761112. Licensed CC0.

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