# Technology Core - The Center for Innovation in Point-of-Care Technologies for HIV/AIDS and Emerging Infectious Diseases at Northwestern University (C-THAN)

> **NIH NIH U54** · NORTHWESTERN UNIVERSITY · 2023 · $768,805

## Abstract

SUMMARY – TECHNOLOGY (TECH) CORE
The Technology Core of The Center for Innovation in Point-of-Care Technologies for HIV/AIDS and Emerging
Infectious Diseases at Northwestern (C-THAN) will support the development of vital POC and home-based
technology specifically designed for diagnosis and management of HIV/AIDS, related conditions, and emerging
infectious diseases in low- and middle-income countries with emphasis on sub-Saharan Africa. We will support
technology projects specifically designed for low resource settings with low or limited medical infrastructure
such as restricted access to electricity, refrigeration and/or central water supply. A successful test will be: user-
friendly, requiring only local training in its operation and maintenance; manufacturable at low cost with low cost
consumables; rapid result; durable; and contain internal checks of device/assay performance, self-calibration,
and error diagnosis. Projects supported by C-THAN will conform to high priority topics of HIV/AIDS research or
address emerging or re-emerging diseases, be amenable to the conditions of low resource environments, and
have high likelihood of commercialization in developing countries. A unique feature of C-THAN is our
commitment to fostering local technology development in LMICs by providing specific funding opportunities for
home-grown solutions via coordinated efforts to specifically incubate POC technology for HIV care in LMICs.
This goal is supported by our access network of well established and emerging African biomedical engineering
programs through our partners in Nigeria, Tanzania, Mali, Senegal, and South Africa. We will build a robust
pipeline of POC and home-based technology by identifying diagnostic needs, recruiting projects that meet
those needs, monitoring progress made in funded projects, providing services and mentorship to guide
projects to maturity, and facilitating the transfer of technologies to clinical validation. The output will be a
pipeline of products of high clinical impact developed from a well-balanced research portfolio originating from
the C-THAN Technology Core.

## Key facts

- **NIH application ID:** 10762200
- **Project number:** 2U54EB027049-06
- **Recipient organization:** NORTHWESTERN UNIVERSITY
- **Principal Investigator:** SALLY Maureen MCFALL
- **Activity code:** U54 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2023
- **Award amount:** $768,805
- **Award type:** 2
- **Project period:** 2018-09-11 → 2028-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10762200

## Citation

> US National Institutes of Health, RePORTER application 10762200, Technology Core - The Center for Innovation in Point-of-Care Technologies for HIV/AIDS and Emerging Infectious Diseases at Northwestern University (C-THAN) (2U54EB027049-06). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10762200. Licensed CC0.

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