# Administrative Supplement: Population-Based Study of Social Determinants of Health and Quality of Cancer Care in HIV-Associated Cancers

> **NIH NIH P30** · EMORY UNIVERSITY · 2023 · $249,999

## Abstract

PROJECT SUMMARY/ABSTRACT
Advances in anti-retroviral therapy have transformed HIV into a chronic disease. As death from HIV has
decreased for people living with HIV (PLWH), mortality from other chronic diseases of aging, particularly non-
AIDS defining cancers (NADC), has significantly increased. Winship Cancer Institute’s P30 cancer center
support grant and its Community Outreach and Engagement component have identified PLWH as a “Special
Population”, experiencing significant cancer disparities in our catchment area of Georgia. Multiple retrospective
database analyses have reported worse cancer outcomes, including survival, between PLWH vs HIV-
populations, but underlying reasons to explain significant differences in cancer care and survival outcomes more
fully remain to be elucidated. We propose two Specific Aims for this exploratory supplement: 1) generate a
population-based cohort of age- and stage-matched HIV+ and HIV- NHL patients derived from the Georgia
cancer registry; and 2) contact this cohort using established registry protocols and evaluate feasibility and
acceptability of validated tools and methods to investigate social determinants of health and multi-level factors
(patient, clinical, facility, provider, system) that might impact diagnosis, treatment and outcomes for both HIV+
and HIV- cancer cases through a mixed methods study design. These Aims are in alignment with the NIH OAR
research priorities related to HIV-Associated Comorbidities, Coinfections, and Complications that contributes to
increasing understanding of the causes, frequency, and clinical outcomes of HIV-related malignancies, as well
as research to reduce Health Disparities … in treatment outcomes of PLWH. Completion of these Aims will lead
to an extramural grant application to expand preliminary data to other NADC.

## Key facts

- **NIH application ID:** 10764361
- **Project number:** 3P30CA138292-14S1
- **Recipient organization:** EMORY UNIVERSITY
- **Principal Investigator:** Suresh S Ramalingam
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2023
- **Award amount:** $249,999
- **Award type:** 3
- **Project period:** 2009-04-07 → 2028-03-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10764361

## Citation

> US National Institutes of Health, RePORTER application 10764361, Administrative Supplement: Population-Based Study of Social Determinants of Health and Quality of Cancer Care in HIV-Associated Cancers (3P30CA138292-14S1). Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/grant/nih/10764361. Licensed CC0.

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