ADVANCED MICROSCOPY FACILITY (AMF) – PROJECT SUMMARY The ability to visualize the biological processes that contribute to the transformation of a normal human cell into a pathogenic cancer cell can provide cancer researchers with the critical insight that might lead to the development of a new cancer therapy. The overall objective of the Advanced Microscopy Facility (AMF) is to support rigorous and reproducible imaging experiments to help foster these discoveries. To do this, the AMF provides imaging expertise and access to well-maintained, state-of-the-art instrumentation for University of Virginia Cancer Center (UVACC) Members. The AMF personnel provide extensive imaging expertise and support imaging experiments from conception to data interpretation. Finally, the AMF provides training and education in imaging best practices and can serve as a resource for imaging rigor and reproducibility for the cancer research community at UVA.