# MITS - SR Component

> **NIH NIH P30** · UNIVERSITY OF VIRGINIA · 2024 · $81,869

## Abstract

MOLECULAR AND IMMUNOLOGICAL TRANSLATIONAL SCIENCES (MITS) – PROJECT SUMMARY
 The MITS Shared Resource serves as a gateway for the study of both animal models of cancer and
human-derived materials with a suite of skills and analytical techniques that allow University of Virginia Cancer
Center (UVACC) Members to evaluate the impact of investigational agents on the diagnosis or treatment of
cancer. MITS provides access to experts for planning, training, executing, and analyzing experiments that are
run on state-of-the-art instrumentation within this Shared Resource and those available in other UVACC-
supported Shared Resources. MITS instrumentation is located for easy access by UVACC Members.
Instrumentation is run by expert technologists during normal working hours and is available for use by
investigators during non-primetime hours once they have completed appropriate training. This Shared
Resource is an expansion of the Animal Models of Disease Core, which was rated as Excellent during the last
review. Minor comments from the previous review of the resource directed at the utilization of CRISPR-Cas9
technology to replace traditional gene targeting for creating conditional knockout and knock-in alleles have
been addressed. MITS made significant equipment upgrades in the past five years and deepened the
repertoire of patient-derived xenografts (PDX) available to researchers. MITS staff routinely interact with other
UVACC Shared Resources, particularly the Biomolecular Analysis Facility, Biostatistics, Advanced Microscopy
Facility, Flow Cytometry Core, and Biorepository and Tissue Research Facility, all of which help make MITS a
nexus for highly-coordinated and efficient pre-clinical and clinical studies. MITS also is supported by the School
of Medicine (SOM), which further lowers the cost for the UVACC users. MITS is reviewed annually by the
UVACC leadership and the SOM Research Advisory Committee to determine the level of subsidy required to
maintain a revenue neutral core. MITS is competitive in pricing, rapid in service turnout time, and provides
guarantees matching or exceeding the standards set up by comparative shared resources nationally. The
UVACC co-pay provided for Members makes MITS a cost-effective Shared Resource.

## Key facts

- **NIH application ID:** 10766180
- **Project number:** 5P30CA044579-33
- **Recipient organization:** UNIVERSITY OF VIRGINIA
- **Principal Investigator:** STUART S. BERR
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $81,869
- **Award type:** 5
- **Project period:** 1997-09-16 → 2027-01-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10766180

## Citation

> US National Institutes of Health, RePORTER application 10766180, MITS - SR Component (5P30CA044579-33). Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/grant/nih/10766180. Licensed CC0.

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