# UCSD Alzheimer's Disease Research Centers P30

> **NIH NIH P30** · UNIVERSITY OF CALIFORNIA, SAN DIEGO · 2023 · $306,316

## Abstract

Abstract
Alzheimer's disease and related dementias (ADRD) together constitute a paramount and growing public health
issue with tremendous cost and unfathomable aggregate suffering. Unless the diseases can be effectively
treated or prevented, increased prevalence with changing demographics will lead to costs the country will find
difficult to bear. Reflecting this national imperative, the National Alzheimer's Project Act (NAPA) created a
roadmap and goal to impact this disease by 2025. The current proposal for renewed funding of the UCSD
Shiley-Marcos Alzheimer's Disease Research Center (ADRC) explicitly aligns with NAPA and leverages the
center's deep roots and engagement built over the past 35 years. The center's rich academic and community
environment make it well positioned to synergize with the ADC network toward achievement of NAPA goals
and milestones, particularly along the theme of examining heterogeneity of ADRD through the study of models,
markers, and mechanisms in a diverse cohort of volunteers. Specifically, the center proposes work that will
bring world-class advanced translational neurosciences to the study of heterogeneity and diversity in ADRD
using new models and new, tailored community engagement approaches. Including innovative disease in a
dish models fostered by its new iPSC Core, and increased engagement with the Latino Amerindian community
through the establishment of a Latino Core. Efforts are tightly integrated with functions of other cores bolstered
by tremendous resources and experience gained over the center's longstanding existence, while incorporating
the most innovative, disruptive and cutting-edge science available on the multifaceted UCSD campus. The
center will achieve the following overarching aims unifying its broad-based activity in research, education,
engagement, and sharing and synergizing with the ADC network: The center will 1) apply well-developed and
interactive cores to foster cross-disciplinary, integrative, and innovative clinical and translational science, 2)
educate and train a diverse workforce, 3) Provide a hub for scientific and community exchange and support,
optimizing core efforts and synergies to best serve the local and broader patient, caregiver, and research
communities and 4) engage in collaborative research across centers, with special emphasis on applying center
strengths to complement the ADC network and extend its impact.

## Key facts

- **NIH application ID:** 10766603
- **Project number:** 3P30AG062429-05S1
- **Recipient organization:** UNIVERSITY OF CALIFORNIA, SAN DIEGO
- **Principal Investigator:** JAMES B BREWER
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2023
- **Award amount:** $306,316
- **Award type:** 3
- **Project period:** 2019-05-01 → 2024-03-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10766603

## Citation

> US National Institutes of Health, RePORTER application 10766603, UCSD Alzheimer's Disease Research Centers P30 (3P30AG062429-05S1). Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/grant/nih/10766603. Licensed CC0.

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