# Antimicrobial Resistance Training Program in the Texas Medical Center (AMR-TPT)

> **NIH NIH T32** · METHODIST HOSPITAL RESEARCH INSTITUTE · 2024 · $342,204

## Abstract

PROJECT SUMMARY/ABSTRACT
The rise of antibiotic-resistant microorganisms globally has become a critical public health priority due to the
devastating consequences that it may have to the world health and economy. Antibiotic resistance (AMR)
threatens the progress of medicine in all areas, and as such, the issue has reached the highest level of
government, including the Office of the US President and the United Nations. AMR is a top public health
priority for both CDC and WHO and has been designated as the “silent” pandemic. Houston is the home to the
largest cluster of healthcare institutions in the world, the Texas Medical Center (TMC), with more than 9,200
hospital beds and 10 million patient visits per year. The Houston area’s strong history of outstanding infectious
diseases research and training includes a focus on AMR and antibiotic stewardship. The combined efforts of
the recently formed Houston Methodist Center of Excellence for Infectious Diseases and the existing Gulf
Coast Consortium (GCC) for Antimicrobial Resistance have resulted in an active, multidisciplinary and
comprehensive research and educational program amalgamating the endeavors of AMR researchers and
creating the resources, personnel, funding and fertile ground to develop an ambitious, innovative, unparalleled
AMR training program. We propose to establish the AMR Training Program in the Texas Medical Center
(AMR-TPT) that trains postdoctoral scholars, clinical residents/fellows and PharmD fellows from eight
institutions in the TMC (Houston Methodist Research Institute, University of Texas Health Science Center at
Houston, MD Anderson Cancer Center, Baylor College of Medicine, University of Texas Medical Branch, Rice
University, University of Houston, and Institute of Biosciences and Technology of Texas A&M University) on
advanced aspects of AMR research. We will take advantage of the strong administrative expertise of the GCC
on successful T32 programs in other areas and the educational activities already in place, combined with the
expertise of world-class AMR researchers. AMR-TPT seeks to leverage and create resources to train the next
generation of scientists and clinician-scientists (MDs, PhDs and PharmDs) focused on tackling the pressing
AMR public health crisis. The highly collaborative environment provides the perfect opportunity for trainees to
acquire the skills, expertise and intellectual abilities to foster innovative research that has a strong translational
component and could be developed to directly influence patient care. Along with a highly interactive AMR
Foundations course and myriad career/professional development opportunities, the proposed training grant
includes expertise in and a focus on i) molecular basis of resistance, ii) bacterial genomics and bioinformatics,
iii) diagnostics, iv) pharmacological aspects of resistance, v) microbiome science, vi) clinical epidemiology and
biostatistics of AMR and vii) antibiotic stewardship. We believe we are pois...

## Key facts

- **NIH application ID:** 10767543
- **Project number:** 1T32AI179595-01
- **Recipient organization:** METHODIST HOSPITAL RESEARCH INSTITUTE
- **Principal Investigator:** Cesar Augusto Arias
- **Activity code:** T32 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $342,204
- **Award type:** 1
- **Project period:** 2024-07-01 → 2029-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10767543

## Citation

> US National Institutes of Health, RePORTER application 10767543, Antimicrobial Resistance Training Program in the Texas Medical Center (AMR-TPT) (1T32AI179595-01). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10767543. Licensed CC0.

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