# Proteogenomics Shared Resource

> **NIH NIH P30** · UNIVERSITY OF MINNESOTA · 2024 · $79,081

## Abstract

Proteogenomics Shared Resource Summary
Proteogenomics integrates now-readily-available next-generation DNA/RNA sequencing data with high-
resolution mass spectrometry (MS)-based proteomics data to identify and quantify expressed proteins. As a
Developing Shared Resource in the current funding period, Proteogenomics catalyzed numerous new
collaborations, which allowed the development of new tools and workflows. It also contributed to several
successful grant applications.
In the current application, it is proposed as a New Shared Resource. In the coming funding period, we will
continue to offer cutting-edge proteogenomic services to MCC members conducting basic, translational, and
clinical cancer research, guided by these Specific Aims: 1) Offer customizable and flexible workflows for
integrative, quantitative analysis of next-generation sequencing data and MS-based proteomics data to identify
novel protein products underlying cancer; 2) Offer a complete informatics workflow for identifying and
quantifying peptide neoantigens with promise for immuno-therapeutic applications; and 3) Offer validated and
emerging metaproteomics tools and workflows for studies of microbiome contributions to cancer.
The Proteogenomics Shared Resource is led by Director Dr. Tim Griffin (Genetic Mechanisms Program) and
Coordinator Dr. Pratik Jagtap, who are leaders of the Galaxy for proteomics (Galaxy-P) project. Both have long
track records in the application of proteogenomic and metaproteomic informatics to cancer research.
We anticipate that 30 researchers, including 21 MCC members, will use this Resource each year. Access to
the technologies offered by the Proteogenomics Shared Resource is free to users through the Minnesota
Supercomputing Institute. Some support for staff members is requested to allow them to work with MCC
members to design studies and generate preliminary data for grant applications.

## Key facts

- **NIH application ID:** 10768165
- **Project number:** 2P30CA077598-26
- **Recipient organization:** UNIVERSITY OF MINNESOTA
- **Principal Investigator:** TIMOTHY J. GRIFFIN
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $79,081
- **Award type:** 2
- **Project period:** 1998-06-01 → 2029-01-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10768165

## Citation

> US National Institutes of Health, RePORTER application 10768165, Proteogenomics Shared Resource (2P30CA077598-26). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10768165. Licensed CC0.

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