# N3-PREP (Neurology, Neurosurgery, & Neuropathology Pitt Research Education Program)

> **NIH NIH UE5** · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · 2024 · $215,896

## Abstract

Project Summary/Abstract
Physician-neuroscientists are essential for converting the discoveries from the laboratory to diagnostic and
therapeutic strategies for persons burdened by neurologic diseases. Integration of research training during
clinical training years (residency and fellowship) is pivotal to fostering the next generation of physician-
neuroscientists, who are essential to bring the neuro-based discoveries to the bedside. The University of
Pittsburgh (Pitt) has an exceptionally strong neuroscience environment, primed to help address this gap through
the Neurology, Neurosurgery, and Neuropathology Pittsburgh Research Education Program (N3-PREP).
N3-PREP will be based in the Departments of Neurology and Neurosurgery and Division of Neuropathology, with
a focus on trainees with a desire to develop an academic research career in the neurosciences. Our overarching
and long-term goal is to train the next generation of physician-neuroscientists in basic science, translational
science, data science, and clinical (patient-oriented) research through a closely mentored approach, in an
environment ripe with physical and faculty resources across the translational spectrum of neuro-focused
research. Biomedical research is a high priority at Pitt and the neuroscience environment is strong, with faculty
across >20 departments and institutes, and cutting-edge research. Currently at Pitt, the Clinical Translational
Science Institute (CTSI) and Physician Scientist Incubator (PSI) program provide important infrastructure for
training physician-scientists. In addition, career development programs include focused programs for enhancing
inclusion of underrepresented minority groups. Key components of N3-PREP include a well-defined pathway for
each trainee to be paired with a primary mentor and a mentoring committee, a core curriculum, internal study
sections for grant reviews, progress tracking for both the trainee and mentor, and continued support for the
trainee’s progress toward an NIH K mentored-career development award. We will also provide a longitudinal
track beginning in the PGY-1 year to increase the interest of the matriculating residents across participating
departments, transform the culture, and ultimately increase a diverse pool of residents well-prepared to get the
most out of the benefits of direct R25 funding. The core curriculum includes formal training in experimental design
and scientific rigor, statistical methodology, grant writing, presentation skills, DEI principles, and the responsible
conduct of research. Led by multi-Principal Investigators in Neurology, Neurosurgery and Neuropathology and
an Advisory committee, N3-PREP is well supported by commitments from 87 research mentors across 16
departments. Our hypothesis is that N3-PREP will increase the number of well-prepared neuro-focused
physician-scientists from the University of Pittsburgh who will progress to being at the forefront of guiding
innovative neuroscience research, tra...

## Key facts

- **NIH application ID:** 10768833
- **Project number:** 1UE5NS134521-01
- **Recipient organization:** UNIVERSITY OF PITTSBURGH AT PITTSBURGH
- **Principal Investigator:** Constantinos George Hadjipanayis
- **Activity code:** UE5 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $215,896
- **Award type:** 1
- **Project period:** 2024-08-15 → 2029-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10768833

## Citation

> US National Institutes of Health, RePORTER application 10768833, N3-PREP (Neurology, Neurosurgery, & Neuropathology Pitt Research Education Program) (1UE5NS134521-01). Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/grant/nih/10768833. Licensed CC0.

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