PROJECT SUMMARY/ABSTRACT The Perlmutter Cancer Center at NYU Langone Health (PCC) recognizes that achieving diversity of its membership and leadership is not only a moral imperative, but is necessary to maximize progress in cancer prevention and therapy and thereby reduce the cancer burden of an increasingly diverse America. We are committed to developing a workforce that “looks like the community we serve”, a goal that requires a sustained, multi-level, and long-term commitment to develop the leadership potential of current faculty, identify and recruit a diverse cohort of new trainees and faculty, and build a large pipeline of talented younger individuals who will become our colleagues and leaders of the future. The new PCC Diversity, Equity, and Inclusion Core (DEIC) was established to fulfill this commitment by developing an explicit plan to achieve these objectives and monitor progress towards reaching our goals. The mission of DEIC is to engage in measurable actions that ensure that PCC membership and leadership reflect the diversity of the population that we serve, with the ultimate goal of eliminating disparities in the burden of cancer. DEIC is directed by PCC member Joseph Ravenell MD, MS, Associate Professor of Population Health and Medicine, Associate Dean of Diversity & Inclusion, and a nationally recognized leader in health and cancer disparities research. He is aided by Assistant Director Michelle Lightfoot, MD, MPH, whose research interest is in health disparities in gynecologic oncology. The Specific Aims of DEIC are: 1) to enhance the diversity of PCC leadership to include groups nationally underrepresented in the research workforce. 2) to expand the diversity of PCC membership and workforce to reflect the diversity of the population served by PCC, and 3) to increase diversity in the pipeline of future PCC members and workforce through mentorship and training of students, trainees, and allied health professionals. Because diversity, equity, and inclusion are critical to best cancer care and science, DEIC is essential to the PCC mission.