# Research Project - RPL Brown

> **NIH NIH P20** · UNIVERSITY OF IDAHO · 2024 · $331,232

## Abstract

PROJECT SUMMARY/ABSTRACT – RPL BROWN
Obesity, defined as excessive adipose tissue (>30% of body weight for women and >20% of body weight for
men), is a national health crisis impacting individuals of all ages. While body mass index (BMI; body
weight/height2; kg/m2) is the primary measure of obesity in epidemiological studies and medical practice, this
measure fails to identify 50% of those with genuine excess adiposity. Consequently, there is a hidden popula-
tion of individuals with high body fat who are misclassified as nonobese via BMI (healthy BMI considered to be
18.5-24.9 kg/m2). These individuals are described as ‘normal weight obese’ (NWO). NWO individuals likely
have the same elevated risks for comorbidities (e.g., metabolic syndrome, prediabetes, cardiovascular dis-
ease, hypertension, and dyslipidemia) as those correctly classified as obese. The prevalence of body fat mis-
classification among females is likely exaggerated in rural communities, where risk of true obesity is elevated
above national averages. This is in part because people living in rural areas tend to have limited access to
healthcare, fitness facilities, community centers, and evidence-based information regarding nutrition and physi-
cal fitness. Much of Idaho is classified as being in the ‘frontier and remote’ (FAR) West with most (80%) coun-
ties classified as rural. Currently, 31% of Idahoan women are classified as obese based on BMI, a number that
almost certainly underestimates true obesity due to NWO. Our preliminary data show high levels of NWO in
physically active college-aged women living in Idaho, and we hypothesize that rates are much higher in the
general population of women and that this is associated with poor health outcomes. The aims of the study pro-
posed here are significant because they address these important questions and will explore factors associated
with NWO risk. Briefly, we will conduct an epidemiological study of premenopausal women documenting rigor-
ous measurements of dietary intake, physical activity and exercise behaviors, perceptions of body image, body
composition and circumferences, muscular strength and endurance, aerobic fitness, metabolic health, oxida-
tive stress, inflammation, and menstrual health. Additionally, we will compare the physical and physiological
outcomes between NWO and NWL premenopausal females. Our central hypothesis is that premenopausal
females with poor diet quality and avoidance of resistance exercise are more likely to be categorized as NWO,
and that these women have suboptimal physical and physiological health. These aims are innovative and sig-
nificant because they will yield novel data related to lifestyle behaviors most strongly associated with NWO in
premenopausal females living in a rural area. Idaho’s population is representative of similar vast regions
across the entire West, so this study’s ramifications for future targeted interventions have implications for
many. This work is impactful as it wil...

## Key facts

- **NIH application ID:** 10770791
- **Project number:** 1P20GM152304-01
- **Recipient organization:** UNIVERSITY OF IDAHO
- **Principal Investigator:** Ann Frost Brown
- **Activity code:** P20 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $331,232
- **Award type:** 1
- **Project period:** 2024-03-11 → 2029-01-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10770791

## Citation

> US National Institutes of Health, RePORTER application 10770791, Research Project - RPL Brown (1P20GM152304-01). Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/grant/nih/10770791. Licensed CC0.

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