# Assessing the feasibility and acceptability of a Time Restricted Feeding intervention among older adults with Mild Cognitive Impairment

> **NIH NIH R61** · UNIV OF NORTH CAROLINA CHAPEL HILL · 2024 · $508,385

## Abstract

Obesity and related metabolic comorbidities have been associated with more than a 4-fold increased risk of
incident cognitive impairment, including Alzheimer’s disease and related dementias (ADRD). Dysfunctional
metabolic flexibility is increasingly recognized as a critical mechanism linking metabolic risk factors to risk of
cognitive impairment, although few studies portable behavioral strategies to enhance metabolic function among
individuals at risk for ADRD. The present study will examine the feasibility and acceptability of a 12-week time
restricted feeding intervention among individuals with mild cognitive impairment (MCI). Changes in cognitive and
metabolic function will also be examined.

## Key facts

- **NIH application ID:** 10771264
- **Project number:** 5R61AG080615-02
- **Recipient organization:** UNIV OF NORTH CAROLINA CHAPEL HILL
- **Principal Investigator:** Patrick Josey Smith
- **Activity code:** R61 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $508,385
- **Award type:** 5
- **Project period:** 2023-02-01 → 2026-01-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10771264

## Citation

> US National Institutes of Health, RePORTER application 10771264, Assessing the feasibility and acceptability of a Time Restricted Feeding intervention among older adults with Mild Cognitive Impairment (5R61AG080615-02). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10771264. Licensed CC0.

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