# Research Training in Hematology

> **NIH NIH T32** · UNIVERSITY OF WISCONSIN-MADISON · 2024 · $514,765

## Abstract

Our training program brings together twenty-three faculty members from ten departments to focus on two areas
of broad importance for hematology and human disease: vascular biology/inflammation and hematopoietic stem
cell (HSC) biology/bone marrow transplantation (BMT). The primary goal is to train M.D. and Ph.D. scientists in
a multi-disciplinary environment to do sustained, independent research in hematology. Two predoctoral positions
are requested that will be filled from an outstanding pool of Ph.D. and M.D.-Ph.D. students in the highly
competitive graduate programs at the University of Wisconsin (UW). Four postdoctoral positions are requested
to train research track candidates from participating clinical (Medicine, Pediatrics, Surgery) and basic science
Departments of Biochemistry, Biomolecular Chemistry, Cell & Regenerative Biology, Medical Microbiology &
Immunology, Nutritional Sciences, Oncology, and Pathology & Laboratory Medicine. The highly interactive
training faculty cluster into two interest groups: vascular biology/inflammation and HSC biology/BMT. Vascular
biology expertise includes microfluidics, proteomics, lipidomics and metabolomics; cryo-electron microscopy and
structure; neutrophil and innate immune cell biology; zebrafish models of injury/inflammation; in vitro modeling
of blood vessels and cell migration; and murine models of aneurysm, hemostasis and thrombosis. HSC
biology/BMT expertise includes embryonic, induced pluripotent and mesenchymal stem cell biology; epigenetic
regulation of hematopoiesis; genetics of bone marrow failure and cancer predisposition syndromes;
metabolomics of normal immune and blood cancer cells, murine and zebrafish models of hematopoiesis and the
HSC niche; the innate immune response vs. tumors; human immune xenotransplant models in mice; preclinical
models of allogeneic BMT and adoptive cellular therapies; clinical trials and bone marrow imaging. Training
opportunities span basic and clinical investigation; including cutting-edge technologies in genomics, proteomics,
metabolomics, microfluidics, zebrafish and murine disease models, and stem cell transplantation. A strong
emphasis is placed on translational research and multidisciplinary training of clinical investigators. The UW
Institute for Clinical and Translational Research offers didactic and degree programs in clinical investigation,
career development, and mentoring expertise. Our trainees have an excellent record of establishing research
careers. Over the lifespan of the predoctoral program, 19 appointees have completed their Ph.D. degrees. Eight
are in academic faculty or scientist positions, eight are industry scientists, one is a chemistry professor at a
teaching college, and two are in academic post-doctoral positions. Over the past 15 years, 26 post-doctoral
trainees have completed their appointments. These trainees include 14 assistant professors, 4 associate
professors, one full professor, 3 academic scientists, 2 industry scientis...

## Key facts

- **NIH application ID:** 10774949
- **Project number:** 2T32HL007899-26
- **Recipient organization:** UNIVERSITY OF WISCONSIN-MADISON
- **Principal Investigator:** Jane Ellen Churpek
- **Activity code:** T32 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $514,765
- **Award type:** 2
- **Project period:** 1998-07-01 → 2029-04-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10774949

## Citation

> US National Institutes of Health, RePORTER application 10774949, Research Training in Hematology (2T32HL007899-26). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10774949. Licensed CC0.

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