Promoting cognitive screening and assessment post-aneurysmal subarachnoid hemorrhage

NIH RePORTER · NIH · R21 · $172,739 · view on reporter.nih.gov ↗

Abstract

The novel central hypothesis of this proposal is that the Quality of Life in Neurological Disorders (Neuro-QoL), a patient-reported outcome (PRO) battery of questionnaires, can fill this gap in screening for clinical decision-making. Our strong preliminary data demonstrate that the cognitive short form within the Neuro-QoL (NQ-CSF) provides a simple yet critically needed screening tool for use in aSAH survivors; however, this instrument has not yet been tested a) as a benchmark to trigger individual patient referral for in-depth neuropsychological assessment; b) for interpretation in relation to other relevant demographic and clinical information; or c) for interpretation in relation to other Neuro-QoL measures. We respond here to PA-19-053 and NOT-OD-20-079, and the spirit of PAR-22-231, to propose one highly focused aim: Determine the utility of the Neuro-QoL cognition short form (NQ-CSF) as a benchmark to trigger individual patient referral for in-depth clinical neuropsychological assessment. This project is innovative for applying the Neuro-QoL for clinically meaningful cognitive symptom screening and individualized patient referral post-aSAH. The work will have a significant impact by informing new practice guidelines to provide earlier and more accurate assessment of cognitive symptomatology. Lack of such knowledge reduces QoL for patients affected by aSAH.

Key facts

NIH application ID
10789774
Project number
1R21NR021052-01
Recipient
UNIVERSITY OF TENNESSEE HEALTH SCI CTR
Principal Investigator
Ansley Grimes Stanfill
Activity code
R21
Funding institute
NIH
Fiscal year
2024
Award amount
$172,739
Award type
1
Project period
2024-06-11 → 2025-08-04