# The Mathematical Sciences in Obesity Research

> **NIH NIH R25** · TRUSTEES OF INDIANA UNIVERSITY · 2024 · $103,680

## Abstract

Project Summary/Abstract
The mathematical sciences including engineering, statistics, computer science, physics, econometrics, and
mathematics qua mathematics are increasingly being applied to advance our understanding of the causes,
consequences, and alleviation of obesity. These applications go beyond routine approaches easily implemented
in available commercial software. Rather, they increasingly involve computationally demanding tasks,
development of novel analytic methods and software, new derivations, and an exceptional degree of
interdigitation of two or more existing techniques. Moreover, these methods and applications continue to
advance; the techniques and questions today are not identical to those from five years ago and continuing to
refresh curricula is essential. Advances at the interface of the mathematical sciences and obesity research
require bilateral training for investigators in both disciplines. Yet, our existing proven course is, to our knowledge,
the only ongoing resource to provide such training by scientists. Our successful five day short course features
some of the world’s finest scientists working at this interface to fill the unmet need by providing multiple, topic-
driven modules designed to bridge the disciplines. The demand for and success of the course we offered
annually for the last five years is evidenced by the facts that over 100 people have enrolled in our course, that
over 1300 users have accessed our course video archives, and that over a dozen collaborations have resulted
in successful grant applications or peer-reviewed publications from our course participants and faculty. The first
module serves as a common orientation for investigators approaching the interface predominantly from a
quantitative or obesity lens, followed by 8 modules with topics such as modeling weight change using energy
balance, modeling effects in populations, genomic analysis in obesity, modeling behavioral responses to obesity,
sensor and engineering models, and scaling laws and obesity. Lectures are video-recorded and posted to our
course website for free viewing, thereby extending the reach of our course. Because individuals learn best in
complex tasks when they can interact with the material, we include a number of interactive sessions designed
to engage the participants in active learning. These sessions include panel discussion, debates with audience
participation, question and answer periods, and discovery-based learning activities. These have been refined by
us over the prior funding cycle to be those that best serve and are most highly appreciated by our participants.
Senior faculty offer lectures and lead small group and individual consultations with participants on topics such
as grant acquisition and navigating an interdisciplinary career. The new Mathematical sciences in Obesity
Research Excellence (MORE) Prize will engage participants beyond the course to identify an outstanding
publication on quantitative obesity rese...

## Key facts

- **NIH application ID:** 10793557
- **Project number:** 5R25DK099080-11
- **Recipient organization:** TRUSTEES OF INDIANA UNIVERSITY
- **Principal Investigator:** DAVID B ALLISON
- **Activity code:** R25 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $103,680
- **Award type:** 5
- **Project period:** 2013-07-01 → 2026-03-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10793557

## Citation

> US National Institutes of Health, RePORTER application 10793557, The Mathematical Sciences in Obesity Research (5R25DK099080-11). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10793557. Licensed CC0.

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