# Center for Harmonizing and Improving Interventions to Prevent Suicide (CHIIPS)

> **NIH VA I01** · VA BOSTON HEALTH CARE SYSTEM · 2024 · —

## Abstract

Background: The rate of death by suicide has risen by more than 30% in the past 20 years in the U.S. The
rate of death by suicide among U.S. Veterans has risen even faster. Whereas Veterans only constitute 8.5% of
the population, they account for 18% of all suicide deaths among U.S. adults. Although recent declines in
suicide mortality among Veterans may be cause for some hopefulness, they also obscure the dynamics of
suicide mortality and effectiveness of preventive interventions across vulnerable groups. Further, although we
do have methods available to stratify individuals by risk level and interventions that can have positive effects in
terms of reducing suicide attempts, these tools are far from perfect. There is still an urgent need to determine
which available suicide prevention interventions might be the most effective for a given individual at a given
time. Significance: The proposed suicide prevention clinical resource center (SP-CRC) is responsive to
CSRD’s solicitation of applications from VA research facilities to establish an SP-CRC that will serve suicide
prevention investigators by providing highly critical research resources to facilitate programmatic and scientific
needs. The mission of our SP-CRC, the Center for Harmonizing and Improving Interventions to Prevent
Suicide (CHIIPS), will be to advance a precision medicine approach to suicide prevention research. CHIIPS
content area hubs will include Predictive Analytics, Biomarkers, Identification, Screening, Assessment, Social
Determinants/Disparities, Interventions, and (v) Training and Education Innovation and Impact: By
establishing a VA SP-CRC with an explicit focus on promoting precision medicine for suicide prevention, we
will improve individual suicide prevention outcomes, address unsatisfactory response rates for standardized
treatments, promote the incorporation of diverse patient presentations, characteristics, and needs into
treatment plans and suicide prevention research, improve system and population-level outcomes, and increase
efficient use of finite resources (staff, funds, infrastructure). Resources Delivered: At the completion of this
project, we will have provided several resources to the VA suicide prevention research community including: 1)
a portfolio review of VA suicide prevention research portfolio projects on precision medicine, 2) a dataset
repository for use by VA suicide prevention researchers to conduct secondary analyses, 3) the establishment
of precision medicine suicide prevention research postdoctoral fellowships, 4) creation and dissemination of
several recommendations for clinical trials methodology and safety protocols for suicide prevention research,
5) various precision medicine related educational resources for suicide prevention researchers to promote
competent precision medicine suicide prevention research, 6) a statistical and research design consultation
service, 7) funding for precision medicine suicide prevention pilot studies or supp...

## Key facts

- **NIH application ID:** 10793589
- **Project number:** 5I01CX002621-02
- **Recipient organization:** VA BOSTON HEALTH CARE SYSTEM
- **Principal Investigator:** Marianne Goodman
- **Activity code:** I01 (R01, R21, SBIR, etc.)
- **Funding institute:** VA
- **Fiscal year:** 2024
- **Award amount:** —
- **Award type:** 5
- **Project period:** 2023-02-01 → 2025-09-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10793589

## Citation

> US National Institutes of Health, RePORTER application 10793589, Center for Harmonizing and Improving Interventions to Prevent Suicide (CHIIPS) (5I01CX002621-02). Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/grant/nih/10793589. Licensed CC0.

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