# Supplement: Recombinant microRNAs in xenobiotic metabolism and disposition

> **NIH NIH R35** · UNIVERSITY OF CALIFORNIA AT DAVIS · 2023 · $60,000

## Abstract

PROJECT SUMMARY
This Administrative Supplement to ongoing R35GM140835 award is to seek for purchasing a new liquid
chromatograph (LC) system that will be used to determine the purity of novel recombinant microRNAs
(BioRNAs) generated through in vivo fermentation production and accurately quantitate target
xenobiotic/drugs and metabolites in complex biological samples. These studies are critical elements in the
MIRA award which will establish the role and importance of microRNAs in posttranscriptional regulation of
xenobiotic metabolism and disposition.

## Key facts

- **NIH application ID:** 10796456
- **Project number:** 3R35GM140835-03S1
- **Recipient organization:** UNIVERSITY OF CALIFORNIA AT DAVIS
- **Principal Investigator:** Aiming Yu
- **Activity code:** R35 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2023
- **Award amount:** $60,000
- **Award type:** 3
- **Project period:** 2021-06-01 → 2026-03-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10796456

## Citation

> US National Institutes of Health, RePORTER application 10796456, Supplement: Recombinant microRNAs in xenobiotic metabolism and disposition (3R35GM140835-03S1). Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/grant/nih/10796456. Licensed CC0.

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