# The Robert T. Malison Yale-Chulalongkorn Stress, Alcohol Use and Psychopathology Training Program

> **NIH NIH D43** · YALE UNIVERSITY · 2024 · $244,006

## Abstract

Abstract
Psychiatric disorders are a set of chronic, non-communicable diseases (NCDs), a global public health problem
of enormous economic, social, and medical cost to the international community. Stress, alcohol use and other
factors (social and environmental; physical disorders) often exacerbate psychiatric disorders. Low and middle
income and developing countries are disproportionately affected due to both economic disadvantages and the
less well-established institutional infrastructures dedicated to the understanding, treatment and prevention of
psychopathology. We propose a collaborative research training program in the multidisciplinary, translational
research of stress, alcohol use and psychopathology between Faculty of Medicine, Chulalongkorn University in
Bangkok, Thailand (the lead Thai site) Phramongkutklao (PMK) Hospital, also in Bangkok, and Prince of Songkla
University (PSU) in Hat Yai, Thailand; and the Yale University School of Medicine in the U.S. The project is
directed by leaders in Thailand and the US, Dr. Kalayasiri at Chulalongkorn, and Drs. Potenza and Gelernter at
Yale, mPIs for this application. Three major training mechanisms are proposed for Thai trainees, including long-
term (1-2-yr) predoctoral and postdoctoral fellowships, and short-term (1-6 month) fellowships. During the five-
year program, training responsibility increases at Chulalongkorn, PMK, and PSU (as experience builds) and
decreases at Yale. This program builds on an extensive research program in Psychiatry at Yale University School
of Medicine, and on existing training and research collaborations between investigators at Yale and investigators
at Chulalongkorn in the study of the genetics and clinical correlates of psychopathology (especially substance
use disorders) in Thai populations. The program will contribute to the capacity of investigators at Chulalongkorn,
PMK and PSU and more generally in Thailand to conduct state-of-the-art research in interdisciplinary and
translational research in psychiatry through a range of training experiences (genetics, molecular biology, clinical,
developmental, psychopharmacology, clinical trials, neuroimaging, implementation, community, and policy
research); and has strong ongoing potential for clinical translation. The explicit long-term goal of the program will
be to build a critical mass of scientists, health professionals, and academics with expertise and a sustainable
research environment at the collaborating Thai institutions to better understand, treat, and prevent the NCDs of
psychiatric illnesses. This training program is also specifically designed to serve a major public health purpose
by enhancing Thailand’s capacity to confront major health concerns including alcohol and other stress-related
disorders that are unprecedented in Thailand’s history. The context of this program is a long-term research and
training collaboration between Yale and Chulalongkorn that focused on drug dependence which was co-led by
...

## Key facts

- **NIH application ID:** 10799695
- **Project number:** 5D43TW012262-02
- **Recipient organization:** YALE UNIVERSITY
- **Principal Investigator:** JOEL GELERNTER
- **Activity code:** D43 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $244,006
- **Award type:** 5
- **Project period:** 2023-04-01 → 2028-02-29

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10799695

## Citation

> US National Institutes of Health, RePORTER application 10799695, The Robert T. Malison Yale-Chulalongkorn Stress, Alcohol Use and Psychopathology Training Program (5D43TW012262-02). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10799695. Licensed CC0.

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