# Microbiome and Transcriptomics Core (MTC)

> **NIH NIH P20** · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · 2024 · $195,330

## Abstract

ABSTRACT (Microbiome and Transcriptomics Core - MTC) 
Current studies in the area of microbial pathogenesis and immunity require knowledge of whole cell and 
system wide responses to infection of both the host and pathogen. Without proper expertise in state of the art 
technology and analysis tools necessary to gather this information, progress cannot be made at the pace 
required for remaining at the forefront of scientific discovery. The Microbiome and Transcriptomics Core 
(MTC) will serve an integral role in ensuring that our COBRE researchers can properly collect microbiome and 
gene expression data at the highest level of rigor using the most advanced technology and methods. The 
MTC will be an extension of the existing OUHSC Laboratory for Molecular Biology and Cytometry Research 
(LMBCR), an established and well-managed university Core laboratory. The MTC will employ personnel from 
within the LMBCR and INBRE Bioinformatics Core that have extensive experience in the focus areas (next gen 
sequencing methods, including microbiome and RNAseq, and bioinformatics) required for the Junior 
Investigator projects. The MTC will provide whole cell/system wide analysis of gene expression using 
established next generation sequencing and transcriptomics technology and appropriate bioinformatics 
approaches. Support for these applications by the MTC will include pre-project consultation, assistance with 
sample preparation and RNA isolation protocols, wet-bench sample processing, bioinformatics analysis and 
post project data deposition, manuscript preparation, and aid with details necessary for future grant 
applications.

## Key facts

- **NIH application ID:** 10800651
- **Project number:** 5P20GM134973-05
- **Recipient organization:** UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR
- **Principal Investigator:** David W Dyer
- **Activity code:** P20 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $195,330
- **Award type:** 5
- **Project period:** 2020-03-01 → 2025-08-19

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10800651

## Citation

> US National Institutes of Health, RePORTER application 10800651, Microbiome and Transcriptomics Core (MTC) (5P20GM134973-05). Retrieved via AI Analytics 2026-06-01 from https://api.ai-analytics.org/grant/nih/10800651. Licensed CC0.

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