The G-RISE at the University of Puerto Rico Medical Sciences Campus (UPR-MSC) program will support the biomedical Ph.D. programs of the UPR School of Medicine Division of Biomedical Sciences (DBS) and the School of Pharmacy. The goals of the G-RISE at the UPR MSC program are to provide support to pre- doctoral students from underrepresented groups in mentored biomedical and behavioral research, enrich the research environment at the UPR-MSC and enhance the academic offerings of the Ph.D. Programs of the Schools of Medicine and Pharmacy. These goals will be pursued using the following objectives: to develop trainees’ technical and professional skills required to conduct research in a responsible and rigorous manner; to provide training to G-RISE faculty that will help them become more reflective mentors and develop better mentoring strategies; to provide broad didactic opportunities through a dynamic seminar series across biomedical fields that will allow trainees and faculty to acquire state-of-the-art, forefront knowledge needed to advance their chosen field; to provide a strong foundation and operational skills on scientific reasoning, rigorous research design, experimental methods, quantitative and computational approaches, and data analysis and interpretation; to ensure trainees retention, degree completion and transition to research careers. Innovative activities are included, such as a course in Data Rigor and Reproducibility for Biomedical Translational Scientists, fellowship proposal and teaching skills courses. In addition to the activities designed to address the specific objectives we have established to achieve the above stated goals, participating Ph.D. students will attend seminars and/or workshops or courses developed in the DBS that provide instruction in Responsible Conduct in Research during their predoctoral training at the University of Puerto Rico Medical Sciences Campus. The RISE Program will ensure that any material developed under the auspices of its research education program be disseminated broadly, on campus or on the internet.