# Fluorescence tools that illuminate biology and inspire translation

> **NIH NIH R35** · UNIVERSITY OF CALIFORNIA BERKELEY · 2023 · $15,811

## Abstract

Summary (1R35GM134963). Understanding the mechanisms of protein and organelle
function and dysfunction requires dynamic analysis of molecular structures and interactions
in live cells. A long-term goal of my laboratory is to develop tools that reveal these functional
elements and apply them to discover novel a significant biology and molecules with useful
or influential properties. I am drawn to complex, multi-disciplinary problems where chemistry
catalyzes exciting and non-incremental progress. We strive not simply to develop tools but
also apply them in innovative ways. Fluorescence spectroscopy features prominently in the
two research programs described herein. In both, fluorescent tools that we developed using
prior NIGMS support have uncovered influential new biology; this application continues this
development and expands the new biology to benefit human health.

## Key facts

- **NIH application ID:** 10809483
- **Project number:** 3R35GM134963-04S1
- **Recipient organization:** UNIVERSITY OF CALIFORNIA BERKELEY
- **Principal Investigator:** Alanna Schepartz
- **Activity code:** R35 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2023
- **Award amount:** $15,811
- **Award type:** 3
- **Project period:** 2020-02-01 → 2025-01-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10809483

## Citation

> US National Institutes of Health, RePORTER application 10809483, Fluorescence tools that illuminate biology and inspire translation (3R35GM134963-04S1). Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/grant/nih/10809483. Licensed CC0.

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