Project summary Worldwide, ~2.8 billion people are exposed daily to smoke from cooking fires, termed household air pollution (HAP), resulting in an estimated 2.3M deaths and 91.4M disability adjusted life years in 2019. The GRAPHS cohort is longitudinally following mother-child dyads from pregnancy through adolescence to understand how HAP exposures during critical windows influences lifelong health. To realize the maximum scientific potential of the GRAPHS cohort, we will expand and improve data collection around key environmental justice topics such as climate and ambient air pollution; enhance ongoing outreach activities to further strengthen community partnerships and cohort retention; and improve data management to enable broad data sharing. The proposed activities will position the GRAPHS cohort as a significant resource for expanding the environmental health sciences workforce in Ghana and beyond.