# Columbia Diabetes Research Center

> **NIH NIH P30** · COLUMBIA UNIVERSITY HEALTH SCIENCES · 2024 · $1,540,022

## Abstract

The Columbia University Diabetes Research Center promotes diabetes research at the largest academic
medical center in the largest U.S. metropolitan area. The DRC fosters integration with existing institutional
centers of excellence in obesity, atherosclerosis, neurobiology, and cardiovascular biology. It endeavors to
fulfill its mission in an equitable, inclusive manner by fostering equal opportunities for individuals of all genders,
ethnic, and socio-economic extractions. Its scientific themes are: (i) Integrated physiology of insulin action
and resistance; (ii) Diabetes, dyslipidemia, and heart disease; (iii) Pancreas development, beta cell function,
and cellular replacement therapies; (iv) Genetics and immunology of Type 1 Diabetes; (v) Global health, health
disparities, and underserved urban populations. The Biomedical Research Base is comprised of 78 NIH-
funded investigators at Columbia, and 4 associate members at sister institutions in New York City. Total
research funding exceeds $ 81M in annual direct costs, including 91 investigator-initiated NIH grants
directly related to diabetes totaling nearly $56M in annual direct costs. Of these, NIDDK funds 64
projects totaling $18M in annual direct costs. The DRC supports four technical Core Facilities:
Translational Biomarker Analytical Core (TBAC); Advanced Tissue Pathology Imaging Core (ATPIC); Mouse
Metabolic Function & Phenotyping Core (MMFPC); Cytometry & Cell Sorting Core (CCSC). These facilities
have been used to capacity by 66 investigators funded by 102 grants and have supported the award of
45 new grants during the current cycle. Additionally, the DRC provides $250K annually for investigators
through a Pilot & Feasibility Grant Program (PF). During the current cycle, this program supported 13
awardees selected from 90 Letters of Inquiry and 51 complete applications. The 11 recipients of completed PF
awards have applied for 12 new grants and obtained 7, 6 of which are funded by NIH, totaling ~$ 2.8M in
annual direct costs. 11 of 13 funded investigators remain active in diabetes research. The DRC supports a
successful Enrichment Program to increase awareness of diabetes research in the local scientific/academic
and promote regional, national, and international collaborations. The Administrative Core provides logistical
support and programmatic leadership, financial oversight and integration of research efforts, core facilities, and
PF administration. During the current funding cycle, the DRC has endeavored to advance NIDDK’s mission by:
(i) supporting original, innovative and high impact research by its members; (ii) raising awareness of and
interest in clinical and basic diabetes research; (iii) enhancing training and other diabetes-related educational
opportunities; (iv) attracting new investigators to diabetes research; (vi) fostering a collegial environment to
facilitate information exchange; (vii) providing impetus and resources to translate basic science discoveries into
clinical ...

## Key facts

- **NIH application ID:** 10813088
- **Project number:** 5P30DK063608-22
- **Recipient organization:** COLUMBIA UNIVERSITY HEALTH SCIENCES
- **Principal Investigator:** DOMENICO ACCILI
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $1,540,022
- **Award type:** 5
- **Project period:** 2002-09-01 → 2027-12-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10813088

## Citation

> US National Institutes of Health, RePORTER application 10813088, Columbia Diabetes Research Center (5P30DK063608-22). Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/grant/nih/10813088. Licensed CC0.

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