PROJECT SUMMARY (Administrative Core) Achieving an integrated learning health system (LHS) requires leadership and an administrative infrastructure to cultivate learning communities to share knowledge, recruit and retain new LHS scientists, promote community engagement, and to facilitate communication across partner institutions. Expanding on existing infrastructure and partnerships established at the University of Minnesota (UMN) under the Minnesota Learning Health System K12 Mentored Career Development Program (MN-LHS) and its Center for Learning Health System Sciences (MN-CLHSS) and framed by the values of service leadership and shared governance, the Learning Health System Embedded Scientist Training and Research (LHS E-STaR) of the North (LEaRN) Center Administrative Core (AC) will provide leadership and administrative oversight of the LEaRN Center to ensure 1) an equitable governance, administrative and communications infrastructure; 2) coordinated research and educational support; 3) innovative patient-centered outcomes and comparative effectiveness research (PCOR/CER) conducted in learning health systems; 4) innovative programming and support that connects trainees, researchers, community stakeholders, and policy makers in knowledge sharing and application for change; and 5) a rigorous system for program evaluation and improvement that will ensure Center impact. The LEaRN Center AC Leadership Team, composed of senior faculty members from each core institution (UMN, M Health Fairview, M Health Fairview, the Minneapolis VA Health Care System Essentia Health, HealthPartners, and Hennepin Healthcare), will serve under multiple PIs (MPIs) Drs. Timothy Beebe and Genevieve Melton-Meaux. Other members of the leadership team will include the co-directors of the Research Education Core and the Research Data Analysis Core. Notably, the LEaRN AC leadership team has an established history of research collaboration and of providing diverse educational and experiential research and training opportunities to scientists to equip them with the tools and expertise to seamlessly transition to a fully embedded LHS scientist.. The site PIs from the hub partner sites will join the LEaRN AC leadership team in biweekly meetings to promote synergy and integration across institutions to strengthen the academic reach and alignment and impact of LEaRN activities across Minnesota. Overall, the LEaRN AC leadership team will oversee and manage all aspects of the LEaRN Center and the related finances and coordinate all administrative aspects of the Center as well as new initiatives, scholar progress, mentor effectiveness, and program outcomes. The LEaRN AC will also coordinate all internal and external communications, manage all LHS scientist recruitment and retention processes, oversee supportive or corrective actions germane to LHS scientist and mentor performance, and establish and maintain effective interactions with the UMN Clinical and Translational Science Institu...